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Table 2 Univariate and multivariate analysis for CC patients aged < 40

From: Reconsideration of the optimal minimum lymph node count for young colon cancer patients: a population-based study

Characteristics

Univariate analysis

Multivariate analysis

HR [95%CI]

P

HR [95%CI]

P

Nodes examined

< 22

1

0.002

1

< 0.001

≥22

0.67 [0.54–0.84]

0.59 [0.46–0.74]

Gender

Male

1

0.005

1

0.012

Female

1.37 [1.10–1.70]

1.33 [1.07–1.66]

Race

White

1

< 0.001

1

< 0.001

Black

1.64 [1.23–2.18]

1.73 [1.29–2.31]

*Others

1.57 [1.16–2.13]

1.38 [1.01–1.87]

AJCC stage

Stage I

1

< 0.001

1

< 0.001

Stage II

2.87 [1.38–5.99]

2.82 [1.30–5.21]

Stage III

4.63 [3.27–6.45]

4.00 [2.89–6.05]

T stage

T1/T2

1

< 0.001

1

0.001

T3/T4

4.38 [2.69–7.14]

3.10 [1.59–6.07]

N stage

N0

1

< 0.001

1

< 0.001

N1/N2

3.67 [2.82–4.77]

3.25 [2.44–4.86]

Tumor location

Left-sided colon

1

0.858

1

0.148

Right-sided colon

0.98 [0.79–1.22]

1.20 [0.94–1.54]

Histological type

Adenocarcinoma

1

< 0.001

1

0.015

Mucous/signet-ring cell

1.76 [1.36–2.28]

1.49 [1.15–1.94]

Others

2.30 [0.95–5.57]

1.48 [0.60–3.64]

Grade

Grade I/Grade II

1

< 0.001

1

< 0.001

Grade III/Grade IV

2.22 [1.78–2.78]

1.74 [1.38–2.20]

Surgical type

Hemicolectomy

1

0.002

1

0.002

Segmental resection

1.45 [1.15–1.83]

1.52 [1.17–1.97]

Tumor size (cm)

< 5

1

0.027

1

0.486

≥5

1.29 [1.03–1.60]

1.09 [0.86–1.38]

  1. *Others: American Indian/AK Native, Asian/Pacific Islander