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Table 2 Univariate and multivariate analysis for CC patients aged < 40

From: Reconsideration of the optimal minimum lymph node count for young colon cancer patients: a population-based study

Characteristics Univariate analysis Multivariate analysis
HR [95%CI] P HR [95%CI] P
Nodes examined < 22 1 0.002 1 < 0.001
≥22 0.67 [0.54–0.84] 0.59 [0.46–0.74]
Gender Male 1 0.005 1 0.012
Female 1.37 [1.10–1.70] 1.33 [1.07–1.66]
Race White 1 < 0.001 1 < 0.001
Black 1.64 [1.23–2.18] 1.73 [1.29–2.31]
*Others 1.57 [1.16–2.13] 1.38 [1.01–1.87]
AJCC stage Stage I 1 < 0.001 1 < 0.001
Stage II 2.87 [1.38–5.99] 2.82 [1.30–5.21]
Stage III 4.63 [3.27–6.45] 4.00 [2.89–6.05]
T stage T1/T2 1 < 0.001 1 0.001
T3/T4 4.38 [2.69–7.14] 3.10 [1.59–6.07]
N stage N0 1 < 0.001 1 < 0.001
N1/N2 3.67 [2.82–4.77] 3.25 [2.44–4.86]
Tumor location Left-sided colon 1 0.858 1 0.148
Right-sided colon 0.98 [0.79–1.22] 1.20 [0.94–1.54]
Histological type Adenocarcinoma 1 < 0.001 1 0.015
Mucous/signet-ring cell 1.76 [1.36–2.28] 1.49 [1.15–1.94]
Others 2.30 [0.95–5.57] 1.48 [0.60–3.64]
Grade Grade I/Grade II 1 < 0.001 1 < 0.001
Grade III/Grade IV 2.22 [1.78–2.78] 1.74 [1.38–2.20]
Surgical type Hemicolectomy 1 0.002 1 0.002
Segmental resection 1.45 [1.15–1.83] 1.52 [1.17–1.97]
Tumor size (cm) < 5 1 0.027 1 0.486
≥5 1.29 [1.03–1.60] 1.09 [0.86–1.38]
  1. *Others: American Indian/AK Native, Asian/Pacific Islander