Table 2 Associations between shortest telomere tertile and colorectal polyp subtypes
Telomere tertilea 2 & 3 | Telomere tertilea 1 | |||
|---|---|---|---|---|
T/S ratio > =0.58 | T/S ratio < 0.58 | |||
N (%) | N (%) | Unadjusted OR | Adjustedb OR | |
Adenoma-Serrated Outcome | ||||
Controls | 32 (65.3) | 17 (34.7) | REF | REF |
Adenomas | 43 (54.3) | 36 (45.6) | 1.58 (0.75,3.29) | 1.77 (0.81,3.88) |
Serrated | 14 (42.4) | 19 (57.6) | 2.55 (1.03,6.33) | 2.98 (1.15,7.77) |
Both | 14 (50.0) | 14 (50.0) | 1.88 (0.73,4.85) | 1.94 (0.72,5.27) |
P for heterogeneity between Adenomas & Serrated = 0.42 | ||||
Adenoma Outcome | ||||
Controls | 32 (65.3) | 17 (34.7) | REF | REF |
Non-advanced adenoma | 25 (54.4) | 21 (45.7) | 1.58 (0.69,3.61) | 1.63 (0.69,3.86) |
Advanced adenoma | 22 (51.2) | 21 (48.8) | 1.80 (0.78,4.16) | 1.90 (0.76,4.73) |
P for heterogeneity between Advanced & Non-advanced adenomas = 0.71 | ||||
Serrated Outcome | ||||
Controls | 32 (65.3) | 17 (34.7) | REF | REF |
Hyperplastic polyps | 22 (48.9) | 23 (51.1) | 1.97 (0.86,4.51) | 2.24 (0.88,5.70) |
Sessile serrated polyps | 4 (33.3) | 8 (66.7) | 3.76 (0.99,14.3) | 3.82 (0.86,16.86) |
P for heterogeneity between Hyperplastic & Sessile Serrated Polyps = 0.61 | ||||