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Table 2 Associations between shortest telomere tertile and colorectal polyp subtypes

From: Telomere length differences between colorectal polyp subtypes: a colonoscopy-based case-control study

  Telomere tertilea 2 & 3 Telomere tertilea 1
  T/S ratio > =0.58 T/S ratio < 0.58   
  N (%) N (%) Unadjusted OR Adjustedb OR
Adenoma-Serrated Outcome
Controls 32 (65.3) 17 (34.7) REF REF
Adenomas 43 (54.3) 36 (45.6) 1.58 (0.75,3.29) 1.77 (0.81,3.88)
Serrated 14 (42.4) 19 (57.6) 2.55 (1.03,6.33) 2.98 (1.15,7.77)
Both 14 (50.0) 14 (50.0) 1.88 (0.73,4.85) 1.94 (0.72,5.27)
P for heterogeneity between Adenomas & Serrated = 0.42
Adenoma Outcome
Controls 32 (65.3) 17 (34.7) REF REF
Non-advanced adenoma 25 (54.4) 21 (45.7) 1.58 (0.69,3.61) 1.63 (0.69,3.86)
Advanced adenoma 22 (51.2) 21 (48.8) 1.80 (0.78,4.16) 1.90 (0.76,4.73)
P for heterogeneity between Advanced & Non-advanced adenomas = 0.71
Serrated Outcome
Controls 32 (65.3) 17 (34.7) REF REF
Hyperplastic polyps 22 (48.9) 23 (51.1) 1.97 (0.86,4.51) 2.24 (0.88,5.70)
Sessile serrated polyps 4 (33.3) 8 (66.7) 3.76 (0.99,14.3) 3.82 (0.86,16.86)
P for heterogeneity between Hyperplastic & Sessile Serrated Polyps = 0.61
  1. a Telomere tertiles were based on the telomere length distribution among controls only
  2. bModels adjusted for age, gender, race, BMI, smoking, and use of anti-inflammatory drugs