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Table 4 Univariate and multivariate analyses of disease-free survival and overall survival using the Cox proportional hazards model for all patients

From: Prognostic value of Dickkopf-1 and ß-catenin expression in advanced gastric cancer

Characteristics Univariate analysis of DFS Multivariate analysis of DFS
  Hazard ratio 95% CI p-value Hazard ratio 95% CI p-value
Age (> 62 vs. ≤62) 1.251 0.725 - 2.158 0.420    
Sex (female vs male) 1.005 0.544 - 1.856 0.987    
Advanced T stage (pT4 vs. pT2/3) 7.564 2.356 – 24.286 0.001 6.569 2.014 – 21.422 < 0.001
Advanced N stage (pN2/3 vs. pN0/1) 3.544 1.959 – 6.409 < 0.001 2.500 1.359 – 4.601 0.003
Lauren’s classification (diffuse vs. non-diffuse) 1.255 0.680 - 2.317 0.467    
Venous invasion (yes vs. no) 1.940 0.771 - 4.883 0.159    
Tumor grade (poor vs well to moderate) 1.172 0.626 – 2.197 0.619    
Adjuvant chemotherapy (yes vs. no) 1.196 0.687– 2.083 0.526    
High DKK1 (yes vs. no) 2.497 1.421 – 4.386 0.001 2.092 1.180 – 3.708 0.012
  Univariate analysis of OS Multivariate analysis OS
1.934 1.269 - 2.946 0.002 1.820 1.189-2.785 0.006
0.656 0.403 - 1.069 0.091    
3.356 1.825 - 6.170 < 0.001 3.137 1.674 – 5.879 < 0.001
2.174 1.431 - 3.302 < 0.001 1.661 1.074 – 2.568 0.023
1.073 0.690 - 1.668 0.755    
1.763 0.852 - 3.649 0.126    
1.058 0.671 - 1.668 0.808    
0.898 0.596 - 1.355 0.610    
2.509 1.637 – 3.846 < 0.001 2.130 1.370 – 3.312 0.001