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Table 4 Univariate and multivariate analyses of disease-free survival and overall survival using the Cox proportional hazards model for all patients

From: Prognostic value of Dickkopf-1 and ß-catenin expression in advanced gastric cancer

Characteristics

Univariate analysis of DFS

Multivariate analysis of DFS

 

Hazard ratio

95% CI

p-value

Hazard ratio

95% CI

p-value

Age (> 62 vs. ≤62)

1.251

0.725 - 2.158

0.420

   

Sex (female vs male)

1.005

0.544 - 1.856

0.987

   

Advanced T stage (pT4 vs. pT2/3)

7.564

2.356 – 24.286

0.001

6.569

2.014 – 21.422

< 0.001

Advanced N stage (pN2/3 vs. pN0/1)

3.544

1.959 – 6.409

< 0.001

2.500

1.359 – 4.601

0.003

Lauren’s classification (diffuse vs. non-diffuse)

1.255

0.680 - 2.317

0.467

   

Venous invasion (yes vs. no)

1.940

0.771 - 4.883

0.159

   

Tumor grade (poor vs well to moderate)

1.172

0.626 – 2.197

0.619

   

Adjuvant chemotherapy (yes vs. no)

1.196

0.687– 2.083

0.526

   

High DKK1 (yes vs. no)

2.497

1.421 – 4.386

0.001

2.092

1.180 – 3.708

0.012

 

Univariate analysis of OS

Multivariate analysis OS

1.934

1.269 - 2.946

0.002

1.820

1.189-2.785

0.006

0.656

0.403 - 1.069

0.091

   

3.356

1.825 - 6.170

< 0.001

3.137

1.674 – 5.879

< 0.001

2.174

1.431 - 3.302

< 0.001

1.661

1.074 – 2.568

0.023

1.073

0.690 - 1.668

0.755

   

1.763

0.852 - 3.649

0.126

   

1.058

0.671 - 1.668

0.808

   

0.898

0.596 - 1.355

0.610

   

2.509

1.637 – 3.846

< 0.001

2.130

1.370 – 3.312

0.001

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