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Table 3 Correlations between clinicopathologic findings and high DKK1 expression with ß-catenin positivity

From: Prognostic value of Dickkopf-1 and ß-catenin expression in advanced gastric cancer

Clinicopathologic features

High DKK1 and positive ß-catenin

P-value

Yes (%)

35 (22.2)

No (%)

123 (77.8)

Age, years

  > 62

21 (60.0)

58 (47.2)

0.180

  ≤ 62

14 (40.0)

65 (52.8)

 

Sex

 Male

27 (77.1)

86 (69.9)

0.403

 Female

8 (22.9)

37 (30.1)

 

T stage

 T2 /3

11 (31.4)

31 (25.2)

0.462

 T4

24 (68.6)

92 (74.8)

 

N stage

 N0/1

14 (40.0)

73 (59.3)

0.042

 N2/3

21 (60.0)

50 (40.7)

 

Lauren’s classification

 Diffuse type

20 (57.1)

85 (69.1)

0.186

 Non-diffuse type

15 (42.9)

38 (30.9)

 

Tumor grade

 Well/moderate

12 (34.3)

34 (27.6)

0.445

 Poor

23 (65.7)

89 (72.4)

 

Lymphatic invasion

 Yes

28 (80.0)

99 (80.5)

0.949

 No

7 (20.0)

24 (19.5)

 

Vascular invasion

 Yes

3 (8.6)

9 (7.3)

0.805

 No

32 (91.4)

114 (92.7)

 

TNM stage

 I/II

14 (40.0)

54 (43.9)

0.681

 III/IV

21 (60.0)

69 (56.1)