Table 1 Correlation between clinicopathologic findings and DKK1 expression
From: Prognostic value of Dickkopf-1 and ß-catenin expression in advanced gastric cancer
Clinicopathologic features | No. of patients (%) | DKK-1 expression | P-value | |
|---|---|---|---|---|
Low (%) 85 (53.8) | High (%) 73 (46.2) | |||
Age, years | ||||
> 62 | 79 (50.0) | 36 (42.4) | 43 (58.9) | 0.038 |
≤ 62 | 79 (50.0) | 49 (57.6) | 30 (41.1) | |
Sex | ||||
Male | 113(71.5) | 60 (70.6) | 53 (72.6) | 0.780 |
Female | 45 (28.5) | 25 (29.4) | 20 (27.4) | |
T stage | ||||
T2/3 | 42 (26.6) | 24 (28.2) | 18 (24.7) | 0.612 |
T4 | 116 (73.4) | 61 (71.8) | 55 (75.3) | |
N stage | ||||
N0 to N1 | 87 (55.1) | 54 (63.5) | 33 (45.2) | 0.021 |
N2 to N3 | 66 (44.9) | 31 (36.5) | 40 (54.8) | |
Lauren’s classification | ||||
Diffuse type | 105(66.5) | 60 (70.6) | 45 (61.6) | 0.235 |
Non-diffuse type | 53(33.5) | 25 (29.4) | 28 (38.4) | |
Tumor grade | ||||
Well/moderate | 46 (29.2) | 20 (23.5) | 26 (35.6) | 0.095 |
Poor | 112 (71.8) | 65 (76.5) | 47 (64.4) | |
Lymphatic invasion | ||||
Yes | 127 (80.4) | 65 (23.5) | 62 (84.9) | 0.182 |
No | 31 (19.6) | 20 (76.5) | 11 (15.1) | |
Vascular invasion | ||||
Yes | 12 (7.6) | 5 (5.9) | 7 (9.6) | 0.381 |
No | 146 (92.4) | 80 (94.1) | 66 (90.4) | |
TNM stage | ||||
I/II | 68 (43.0) | 41 (51.8) | 27 (37.0) | 0.155 |
III/IV | 90 (57.0) | 44 (48.2) | 46 (63.0) | |