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Table 1 Correlation between clinicopathologic findings and DKK1 expression

From: Prognostic value of Dickkopf-1 and ß-catenin expression in advanced gastric cancer

Clinicopathologic features No. of patients (%) DKK-1 expression P-value
Low (%)
85 (53.8)
High (%)
73 (46.2)
Age, years
  > 62 79 (50.0) 36 (42.4) 43 (58.9) 0.038
  ≤ 62 79 (50.0) 49 (57.6) 30 (41.1)  
Sex
 Male 113(71.5) 60 (70.6) 53 (72.6) 0.780
 Female 45 (28.5) 25 (29.4) 20 (27.4)  
T stage
 T2/3 42 (26.6) 24 (28.2) 18 (24.7) 0.612
 T4 116 (73.4) 61 (71.8) 55 (75.3)  
N stage
 N0 to N1 87 (55.1) 54 (63.5) 33 (45.2) 0.021
 N2 to N3 66 (44.9) 31 (36.5) 40 (54.8)  
Lauren’s classification
 Diffuse type 105(66.5) 60 (70.6) 45 (61.6) 0.235
 Non-diffuse type 53(33.5) 25 (29.4) 28 (38.4)  
Tumor grade
 Well/moderate 46 (29.2) 20 (23.5) 26 (35.6) 0.095
 Poor 112 (71.8) 65 (76.5) 47 (64.4)  
Lymphatic invasion
 Yes 127 (80.4) 65 (23.5) 62 (84.9) 0.182
 No 31 (19.6) 20 (76.5) 11 (15.1)  
Vascular invasion
 Yes 12 (7.6) 5 (5.9) 7 (9.6) 0.381
 No 146 (92.4) 80 (94.1) 66 (90.4)  
TNM stage
 I/II 68 (43.0) 41 (51.8) 27 (37.0) 0.155
 III/IV 90 (57.0) 44 (48.2) 46 (63.0)