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Table 3 Details of trials included in IAC or IVC treatment based on RE grading

From: Comparison between intravenous chemotherapy and intra-arterial chemotherapy for retinoblastoma: a meta-analysis

Authors

Primary treatment

Mean follow -up

(months)

Globe salvage in different group eyes (%)

Overall success rate (%)

I-III

IV

V

Gombos2002

IVC

33.0

84.8(28/32)

50(1/2)

62.5(5/8)

81.0(34/42)

Brichard2002

IVC

21.0

100.0(12/12)

NA

57.1(12/21)

72.7(24/33)

Kim2003

IVC

13.0

85.7(12/14)

71.4(5/7)

66.7(4/6)

77.8(21/27)

Abramson2008

IAC

9.0

NA

NA

77.8(7/9)

77.8(7/9)

Abramson2010

IAC

15.0

100.0(2/2)

100.0(1/1)

96.0(24/25)

96.4(27/28)

Gobin2011

IAC

24.0

100.0(8/8)

100.0(4/4)

80.6(29/36)

85.4(41/48)

Shields2011

IAC

24.0

100.0(2/2)

100.0(5/5)

83.3(5/6)

92.3(12/13)

  1. Note: Globe salvage: avoidance of enucleation or EBRT. Abbreviations: IVC = intravenous chemotherapy; IAC = intra-arterial chemotherapy; NA = not applicable