Fig. 6From: NLRP3 promotes tumor growth and metastasis in human oral squamous cell carcinomaNLRP3 knockdown reduced OSCC cell growth in vivo. WSU-HN6 cells with or without NLRP3 knockdown were implanted into nude mice as described in Materials and methods. a Tumor volumes of each group at different time points. b Representative image of tumors derived from mice in each group. c Tumor weights of the three groups. d NLRP3 and IL-1β expression in tumors derived from parental cells, mock vector-transfected cells and shNLRP3-transfected cells were determined by IHC staining (original magnification 200×). Six mice were included for each group, and one representative experiment out of three is shown. (*P < 0.05, **P < 0.01)Back to article page