From: NKX2.5 is expressed in papillary thyroid carcinomas and regulates differentiation in thyroid cells
Variable | Category | No. of cases | % of cases |
---|---|---|---|
Gender | Male | 10 | 19.6 |
Female | 41 | 80.4 | |
Age | ā¤40Ā years | 23 | 45.1 |
41ā60Ā years | 11 | 21.6 | |
>ā60Ā years | 17 | 33.3 | |
Type of surgery | Total or near total thyroidectomy | 42 | 82.4 |
Partial thyroidectomy | 7 | 13.7 | |
Others | 2 | 3.9 | |
Neck dissection | Yes | 27 | 52.9 |
No | 24 | 47.1 | |
Tumour size | ā¤4Ā cm | 43 | 84.3 |
>ā4Ā cm | 8 | 15.7 | |
Pathological stage of primary tumor size (pT) | pT1 and pT2 | 22 | 43.1 |
pT3 and pT4 | 28 | 54.9 | |
pTx | 1 | 2.0 | |
Pathological stage of regional lymph node (pN) | pN1 | 30 | 58.8 |
pN2 | 3 | 5.9 | |
pNx | 18 | 35.3 | |
Pathological stage of distant metastasis (pM) | pM0 | 42 | 82.4 |
pM1 | 9 | 17.6 | |
Pathological stage (pTNM) | pTNM I | 22 | 43.1 |
pTNM II | 3 | 5.9 | |
pTNM III | 4 | 7.8 | |
pTNM IV | 15 | 29.4 | |
Unknown | 7 | 13.8 | |
Histopathological classification | Classic papillary carcinoma | 40 | 78.2 |
Follicular variant | 5 | 9.8 | |
Tall cell variant | 2 | 4.0 | |
Clear cell variant | 1 | 2.0 | |
Solid variant | 1 | 2.0 | |
Oncocytic variant | 1 | 2.0 | |
Others | 1 | 2.0 | |
Extrathyroid extravasation | Yes | 30 | 58.8 |
No | 18 | 35.3 | |
Unknown | 3 | 5.9 | |
Vascular or angiolymphatic invasion | Yes | 23 | 45.1 |
No | 22 | 43.1 | |
Unknown | 6 | 11.8 | |
Morbidity outcome | Without recurrence or persistence | 21 | 41.2 |
Recurrence | 9 | 17.6 | |
Persistence | 21 | 41.2 | |
Place of outcome | Without recurrence or persistence | 21 | 41.2 |
Local and/or regional lesion only | 11 | 21.6 | |
Distant metastasis only | 8 | 15.7 | |
Both (Local and regional lesion and distant metastasis) | 10 | 19.6 | |
Unknown | 1 | 1.9 | |
Lethality within 10Ā years follow-up | Yes | 8 | 15.7 |
No | 43 | 84.3 | |
Cause of death | PTC | 6 | 75 |
Others | 2 | 25 |