Table 1 Characteristics of patients with ALL according to NUDT15 genotype
|  |  | NUDT15 (rs116855232, c.415C > T) | ||
|---|---|---|---|---|
Total patients | CC | CT | TT | |
| Â | 74 | 29 | 2 | |
Sex | ||||
 Male | 66 (62.9%) | 48 | 16 | 2 |
 Female | 39 (37.1%) | 26 | 13 | 0 |
Age(/year) | 5.8 (1.1~ 14.0) | 5.8 (1.0~ 14.0) | 5.5 (2.0~ 14.0) | 6.8 (4.0~ 9.0) |
BSA(/m2) | 0.82 (0.48~ 1.53) | 0.81 (0.48~ 1.33) | 0.79 (0.49~ 1.53) | 1.33 (1.21~ 1.46) |
Risk group | ||||
 standard-risk | 67 (63.8%) | 46 | 19 | 2 |
 median-risk | 38 (36.2%) | 28 | 10 | 0 |
Immunologic subtype | ||||
 B cell | 101 | 73 | 26 | 2 |
 T cell | 4 | 1 | 3 | 0 |
TPMT 719 A > G | ||||
 *1/*1 | 99 | 69 | 30 | 0 |
 *1/*3C | 6 | 5 | 1 | 0 |
ITPA 94C > A | ||||
 CC | 68 | 49 | 17 | 2 |
 CA | 36 | 24 | 12 | 0 |
 AA | 1 | 1 | 0 | 0 |