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Table 1 Characteristics of patients with ALL according to NUDT15 genotype

From: Optimal predictor for 6-mercaptopurine intolerance in Chinese children with acute lymphoblastic leukemia: NUDT15, TPMT, or ITPA genetic variants?

   NUDT15 (rs116855232, c.415C > T)
Total patients CC CT TT
  74 29 2
Sex
 Male 66 (62.9%) 48 16 2
 Female 39 (37.1%) 26 13 0
Age(/year) 5.8 (1.1~ 14.0) 5.8 (1.0~ 14.0) 5.5 (2.0~ 14.0) 6.8 (4.0~ 9.0)
BSA(/m2) 0.82 (0.48~ 1.53) 0.81 (0.48~ 1.33) 0.79 (0.49~ 1.53) 1.33 (1.21~ 1.46)
Risk group
 standard-risk 67 (63.8%) 46 19 2
 median-risk 38 (36.2%) 28 10 0
Immunologic subtype
 B cell 101 73 26 2
 T cell 4 1 3 0
TPMT 719 A > G
 *1/*1 99 69 30 0
 *1/*3C 6 5 1 0
ITPA 94C > A
 CC 68 49 17 2
 CA 36 24 12 0
 AA 1 1 0 0