Fig. 2From: Optimal predictor for 6-mercaptopurine intolerance in Chinese children with acute lymphoblastic leukemia: NUDT15, TPMT, or ITPA genetic variants?Combined effects of NUDT15 and TPMT on 6-MP dose intensity. a Patients were classified based on NUDT15 and TPMT genotypes. b Patients were classified as 0, 1 and 2 according to the number of risk alleles in NUDT15 and TPMT. A strong correlation was shown between the burden of risk alleles and dose intensity (P = 0.0049)Back to article page