Fig. 7

PAX6 KO cells respond differently to treatment with the chemotherapeutic drugs TMZ, WA and SFA compared to WT cells. U251 N PAX6 KO and WT cells were treated with 250 μM Temozolomide (TMZ), 1.5 μM Withaferin A (WA) and 10 μM Sulforophane (SFA) for 48 (WA and SFA) or 72 (TMZ) hours and analyzed for apoptosis by anti-Annexin/PI staining and FACS. The experiment shown is representative of three independent experiments