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Fig. 1 | BMC Cancer

Fig. 1

From: HPV-16 E7 expression up-regulates phospholipase D activity and promotes rapamycin resistance in a pRB-dependent manner

Fig. 1

HPV-16 E7 expression increases PLD expression and activity. a PLD expression levels were analyzed by Western-blot in PHK transduced with empty vector, HPV-16 E6E7, wild-type E7 or E7 mutants E7E26G and E7CVQ68-70AAA. b PLD activity was determined by trans-phosphatidylation reaction in the presence of 1-butanol. Generation of phosphatidylbutanol (PtBt) indicates increased PLD activity. PLD activity was normalized to that in pLXSN transduced cells, which was given an arbitrary value of 1

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BMC Cancer

ISSN: 1471-2407

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