Fig. 6

PCNP mediates the MAPK pathway in human neuroblastoma cells. a Western blotting analysis of the expressions of ERK1/2, ERK1/2 (Thr202/Tyr204), p38, p38 (Thr180/Tyr182), JNK, and p-JNK (Thr183/Tyr185) in SH-SY5Y and SK-N-SH cells. GAPDH was used as the loading control. b, c The intensities of the bands were quantified by densitometry analyses and normalized by the amount of ERK, p38, or JNK. Data are presented as mean ± SEM of three independent experiments; *P < 0.05, **P < 0.01 compared with the Mock group; #P < 0.05, ##P < 0.01 compared with the sh-Scb group