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Fig. 5 | BMC Cancer

Fig. 5

From: PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways

Fig. 5

Effects of PCNP on the expressions of Bcl-2 family proteins in human neuroblastoma cells. a Western blotting analysis of the expressions of Bax, Bcl-2, Bad, and Bcl-xl in SH-SY5Y and SK-N-SH cells. GAPDH was used as the loading control. (b, c) The densitometry analysis of each factor was performed, normalized to the corresponding GAPDH level. The expression ratios of Bax/Bcl-2 and Bad/Bcl-xL were quantified. Data are presented as mean ± SEM of three independent experiments; *P < 0.05, **P < 0.01 compared with the Mock group; #P < 0.05, ##P < 0.01 compared with the sh-Scb group

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