Fig. 2
From: Reduction of MHC-I expression limits T-lymphocyte-mediated killing of Cancer-initiating cells
TC-1 CICs are more resistant to CTL-mediated immune responses than non-CICs. a CTL assay (representative of three independent experiments) demonstrating non-CICs are more efficiently lysed than CICs by primed splenocytes at each effector to target (E:T) cell ratio (n = 3). b Enhanced IFN-γ release, as assessed by ELISA, 72-h after co-culture of primed splenocytes and mitomycin C treated non-CICs compared to co-culture with mitomycin C treated CICs, n = 8. Error bars are standard deviation. **P ≤ 0.001, *P = 0.004