Fig. 4

Evaluation of the value of the common genes in building breast cancer subtyping classifier. a 1141 METABRIC samples including 144 normal breast tissue samples were clustered by the 62 common genes that shared by at least three signatures using 2D Euclidean clustering with complete linkage settings. The clusters were selected by level 3 or 4 branches. Nine clusters were selected (C1 to C9) including the normal sample cluster C1. The PAM50 subtypes were indicated under the nine cluster colour bars. b Kaplan-Meier survival analysis for the nine subgroups. The disease specific survival (DSS) time was used for outcome endpoint