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Table 1 Clinopathological characteristics of the 44 patients with AIS of the cervix who were treated with LEEP

From: Oncological and reproductive outcomes of adenocarcinoma in situ of the cervix managed with the loop electrosurgical excision procedure

Parameters Number of patients Percent (%)
Age at diagnosis, (Mean;range) 36.1 ± 14.2 (28–55)
Baseline parity
 Nulliparous 14 31.8
 Pluriparous 30 68.2
Presentation
 Contact bleeding 2 4.5
 Vaginal discharge 1 2.3
 Asymptomatic 41 93.2
Referral Cytology
 ASCUS 13 29.5
 AGC 4 9.1
 LSIL 8 18.2
 HSIL 13 29.5
 AIS 1 2.3
 NILM 5 11.4
High-risk HPV
 Negative 4 9.1
 Positive 39 88.6
 Unkonwn 1 2.3
Height of LEEP specimens(cm; range) 1.1 ± 0.2 (0.7–2)
Depth of LEEP specimens(cm; range) 1.5 ± 0.3 (1–2)
Status of LEEP margin
 Negative 33 70.5
 Positive 10 29.5
 Not evaluable 1 2.3
AIS detected by
 Papanicolaou test 1 2.3
 Punch biopsy 12 27.3
 LEEP only 31 70.5
Multifocality
 Yes 4 9.1
 No 40 90.9
Coexisting squamous disease
 CIN I 5 11.4
 CIN II 8 18.2
 CIN III 25 54.5
Absent 6 13.6
Follow-up (month;range) 36.9 ± 18.7 (3–101)
Status at the last contact
 Abnormal cytology 1 2.3
 Positive high-risk HPV 6 13.6
 Both positive 1 2.3
 Both negative 36 81.8
  1. Note:AIS adenocarcinoma in situ, LEEP loop electrosurgical excisional procedure, ASCUS atypicai squamous cells, AGC,atypical glandular cell, HSIL high-grade squamous intraepithelial lesions, NILM negative for intraepithelial lesion or malignancy, CIN cervical intraepithelial lesion