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Table 1 Clinopathological characteristics of the 44 patients with AIS of the cervix who were treated with LEEP

From: Oncological and reproductive outcomes of adenocarcinoma in situ of the cervix managed with the loop electrosurgical excision procedure

Parameters

Number of patients

Percent (%)

Age at diagnosis, (Mean;range)

36.1 ± 14.2 (28–55)

Baseline parity

 Nulliparous

14

31.8

 Pluriparous

30

68.2

Presentation

 Contact bleeding

2

4.5

 Vaginal discharge

1

2.3

 Asymptomatic

41

93.2

Referral Cytology

 ASCUS

13

29.5

 AGC

4

9.1

 LSIL

8

18.2

 HSIL

13

29.5

 AIS

1

2.3

 NILM

5

11.4

High-risk HPV

 Negative

4

9.1

 Positive

39

88.6

 Unkonwn

1

2.3

Height of LEEP specimens(cm; range)

1.1 ± 0.2 (0.7–2)

Depth of LEEP specimens(cm; range)

1.5 ± 0.3 (1–2)

Status of LEEP margin

 Negative

33

70.5

 Positive

10

29.5

 Not evaluable

1

2.3

AIS detected by

 Papanicolaou test

1

2.3

 Punch biopsy

12

27.3

 LEEP only

31

70.5

Multifocality

 Yes

4

9.1

 No

40

90.9

Coexisting squamous disease

 CIN I

5

11.4

 CIN II

8

18.2

 CIN III

25

54.5

Absent

6

13.6

Follow-up (month;range)

36.9 ± 18.7 (3–101)

Status at the last contact

 Abnormal cytology

1

2.3

 Positive high-risk HPV

6

13.6

 Both positive

1

2.3

 Both negative

36

81.8

  1. Note:AIS adenocarcinoma in situ, LEEP loop electrosurgical excisional procedure, ASCUS atypicai squamous cells, AGC,atypical glandular cell, HSIL high-grade squamous intraepithelial lesions, NILM negative for intraepithelial lesion or malignancy, CIN cervical intraepithelial lesion