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Table 2 Dose intensity and cumulative dosage for the dose-reduction and full dosage subgroups

From: Chemotherapy for metastatic colon cancer: No effect on survival when the dose is reduced due to side effects

 

Substance

Dose group

Mean in mg

standard deviation

p-value

Cumulative Dosage

5-Fluorouracil

100%

54,934

55,617

0.42

< 80%

64,321

61,824

Oxaliplatin

100%

1046

852

0.34

< 80%

1245

976

Irinotecan

100%

2861

3295

0.77

< 80%

3099

3296

Dose intensity

5-Fluorouracil

100%

5383

1450

0.002

< 80%

4547

1178

Oxaliplatin

100%

173

31

0.03

< 80%

156

35

Irinotecan

100%

311

74

0.04

< 80%

274

65

  1. P-values were calculated with t-test