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Table 2 Dose intensity and cumulative dosage for the dose-reduction and full dosage subgroups

From: Chemotherapy for metastatic colon cancer: No effect on survival when the dose is reduced due to side effects

  Substance Dose group Mean in mg standard deviation p-value
Cumulative Dosage 5-Fluorouracil 100% 54,934 55,617 0.42
< 80% 64,321 61,824
Oxaliplatin 100% 1046 852 0.34
< 80% 1245 976
Irinotecan 100% 2861 3295 0.77
< 80% 3099 3296
Dose intensity 5-Fluorouracil 100% 5383 1450 0.002
< 80% 4547 1178
Oxaliplatin 100% 173 31 0.03
< 80% 156 35
Irinotecan 100% 311 74 0.04
< 80% 274 65
  1. P-values were calculated with t-test