TY - JOUR AU - Munker, Stefan AU - Gerken, Michael AU - Fest, Petra AU - Ott, Claudia AU - Schnoy, Elisabeth AU - Fichtner-Feigl, Stefan AU - Wiggermann, Philipp AU - Vogelhuber, Martin AU - Herr, Wolfgang AU - Stroszczynski, Christian AU - Schlitt, Hans Jürgen AU - Evert, Matthias AU - Reng, Michael AU - Klinkhammer-Schalke, Monika AU - Teufel, Andreas PY - 2018 DA - 2018/04/23 TI - Chemotherapy for metastatic colon cancer: No effect on survival when the dose is reduced due to side effects JO - BMC Cancer SP - 455 VL - 18 IS - 1 AB - 5-Fluorouracil (5FU), Folinic acid (FA), and Oxaliplatin (FOLFOX) or 5FU, FA, and Irinotecan (FOLFIRI) are standard regimens for palliative chemotherapy of metastatic colon cancer. Since data showing the influence of dose reduction in palliative treatment are rare, the objective of this single center, retrospective study was to further characterize the influence of dose reduction on efficacy of these therapeutic regimens. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-018-4380-z DO - 10.1186/s12885-018-4380-z ID - Munker2018 ER -