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Table 5 Multivariate Cox regression analysis of association of various clinical factors with overall survival in melanoma patients with brain metastasis

From: Survival and clinical outcomes of patients with melanoma brain metastasis in the era of checkpoint inhibitors and targeted therapies

Variable Chi-squared Hazard ratio P value
Gender 0.89 1.93 0.35
Presence of cerebellar metastasis 6.74 4.61 0.009*
Number of brain metastases 0.60 0.93 0.44
Presence of adrenal Metastasis 4.89 9.94 0.027*
Craniotomy 4.45 0.27 0.035*
Stereotactic radiosurgery 0.92 0.51 0.34
Treated with whole brain radiation therapy 1.08 2.13 0.298
Treatment with anti-PD-1 antibody 3.68 0.34 0.055
  1. *p-value is < 0.05