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Table 1 Data from the seven patient cohorts

From: Cholesterol synthesis pathway genes in prostate cancer are transcriptionally downregulated when tissue confounding is minimized

Abbreviation

Source

Dataset reference

Article reference

Analysis Platform

Samples

PCa

Normal

Unique genes

HP on all samples

Bertilsson

Array Express

E-MTAB-1041

[27]

Microarray, A-MEXP-2087 - Illumina Human HT-12 WG-DASL

156

116

40

14,149

Yes

Chen

GEO

GSE8218

[21, 28]

Microarray, Affymetrix Human Genome U133A Array

136

65

71

12,497

Yes

Taylor

GEO

GSE21034

[29]

Microarray, Affymetrix Human Exon 1.0 ST Array

160

131

29

18,294

No

TCGA

TCGA

TCGA

[30]

RNA-Seq, Illumina HiSeq 2000/ Genome Analyzer IIX

549

497

52

20,504

No

Prensner

dbGaP

phs000443. v1.p1

[31]

RNA-Seq, Illumina Genome Analyzer

116

78

38

23,712

No

Sboner

GEO

GSE16560

[35]

Microarray, Human 6 k Transcriptionally Informative Gene Panel for DASL.

281

281

0

6102

No

Erho

GEO

GSE46691

[36]

Exon array, Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]

545

545

0

17,163

No

  1. Footnote: HP histopathology, GEO gene expression omnibus, TCGA the cancer genome atlas, dbGap the database of genotypes and phenotypes, PCa prostate cancer