Skip to main content

Advertisement

Table 1 Patient Characteristics at Baseline (N = 433)

From: Incidence, pattern and prognosis of brain metastases in patients with metastatic triple negative breast cancer

Characteristics No. Percentage (%)
Age, years
 Median (Range) 48 (23–78)
  ≤ 40 97 22.2
  > 40 336 77.8
Menopausal status
 Pre- or perimenopause 286 66.0
 Postmenopause 138 31.9
 Unknown 9 2.1
Histological subtype
 Invasive ductal 419 96.8
 Lobular 6 1.4
 Metaplastic 6 1.4
 Medullary 2 0.5
Grade
 I-II 100 23.1
 III 333 76.9
DFI
  ≤ 1 year 114 26.3
  > 1 year 267 61.7
 IV 52 12.0
Prior neo/adjuvant chemotherapy
 Anthracycline-containing regimen 323 84.8
 Anthracycline and Taxanes regimen 268 70.3
 Cyclophosphamide 340 89.2
Initial site of mTNBC
 Lymph nodes 247 57
 Liver 101 23.3
 Lung 183 42.3
 Bone 105 24.3
 Pleural effusion 52 12
 Local recurrence 105 24.2
 Brain 32 7.4
 Contralateral breast 2 0.5
Visceral metastasis
 Yes 252 58.2
 No 181 41.8
Number of metastatic organ sites
  ≥ 3 37 8.5
  < 3 396 91.5
  1. DFI disease free interval