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Table 1 Patient Characteristics at Baseline (N = 433)

From: Incidence, pattern and prognosis of brain metastases in patients with metastatic triple negative breast cancer

Characteristics

No.

Percentage (%)

Age, years

 Median (Range)

48 (23–78)

  ≤ 40

97

22.2

  > 40

336

77.8

Menopausal status

 Pre- or perimenopause

286

66.0

 Postmenopause

138

31.9

 Unknown

9

2.1

Histological subtype

 Invasive ductal

419

96.8

 Lobular

6

1.4

 Metaplastic

6

1.4

 Medullary

2

0.5

Grade

 I-II

100

23.1

 III

333

76.9

DFI

  ≤ 1 year

114

26.3

  > 1 year

267

61.7

 IV

52

12.0

Prior neo/adjuvant chemotherapy

 Anthracycline-containing regimen

323

84.8

 Anthracycline and Taxanes regimen

268

70.3

 Cyclophosphamide

340

89.2

Initial site of mTNBC

 Lymph nodes

247

57

 Liver

101

23.3

 Lung

183

42.3

 Bone

105

24.3

 Pleural effusion

52

12

 Local recurrence

105

24.2

 Brain

32

7.4

 Contralateral breast

2

0.5

Visceral metastasis

 Yes

252

58.2

 No

181

41.8

Number of metastatic organ sites

  ≥ 3

37

8.5

  < 3

396

91.5

  1. DFI disease free interval