Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 1 Baseline characteristics of patients scheduled for PIPAC/PITAC

From: Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for the treatment of malignant mesothelioma

Characteristics/Data items Number Percent
Total patients 29 100
Sex
 - Male 17 58.6
 - Female 12 41.4
Mean age (years; range) 62.4 (42 to 84)  
ECOG performance score
 - 0 or 1 26 89.7
 - 2 or 3 3 10.3
Karnofsky Index
 - 100% 2 6.9
 - 90% 15 51.7
 - 80% 9 31.0
 - 70% 2 6.9
 - 60% 1 3.4
Mesothelioma cell type
 - epithelioid 29 100
Clinical type
 - “dry” type 8 27.6
 - “wet” type 12 41.4
 - “mixed” type 9 31.0
Alcohol consumption
 - no or minimal 22 75.9
 - daily alcohol intake 7 24.1
Smoking habits
 - no 18 62.0
 - yes 11 38.0
Primary tumor site at initial diagnosis
 - abdominal 24 82.8
 - thoracal 5 17.2
Prior extended resection surgery
 - cytoreduction & HIPEC (CC-0 & CC-1) 7 24.1
 - abdominal debulking 8 27.6
 - pleuropneumonectomy 2 6.9
 - thoracotomy/decortication 3 10.3
Prior surgical score (PSS)
 - PSS 0 11 27.5
 - PSS 1 8 29
 - PSS 2 6 15
 - PSS 3 15 37.5
Extra-abdominal metastatic spread before PIPAC/PITAC 13 44.8
 - thoracal 8 27.6
 - mediastinal 3 10.3
 - abdominal wall 2 6.9
No previous systemic chemotherapy 8 27.6
 - refused any systemic chemotherapy 3 10.3
 - stop due to severe side effects 3 10.3
 - new diagnosis of disease 2 6.9
First line chemotherapy 21 72.4
 - Cisplatin & Pemetrexed 17 58.6
 - Pemetrexed mono 3 10.3
 - Carboplatin & Pemetrexed 1 3.4
Second line chemotherapy 8 27.6
 - Cisplatin & Pemetrexed 5 17.2
 - Pemetrexed mono 3 10.3
Third line chemotherapy 2 6.9
 - Pemetrexed mono 2 6.9
Systemic chemotherapy & scheduled for PIPAC 7 24.1
 - Cisplatin & Pemetrexed 4 13.8
 - Pemetrexed mono 3 10.3
Scheduled for PIPAC without systemic chemotherapy 22 75.9
  1. HIPEC hyperthermic intraperitoneal chemotherapy, ECOG Eastern Conference Oncology Study Group, PIPAC Pressurized IntraPeritoneal Aerosol Chemotherapy, PITAC Pressurized IntraThoracal Aerosol Chemotherapy, PSS prior surgical score, “wet” type = presence of ascites, “dry” = type absence of ascites