Table 1 Legend: Baseline characteristics for both groups. Group A: Fasting for the first half of cycles of chemotherapy and eating a normocaloric diet for the second half of cycles; Group B: Eating a normocaloric diet for the first half of cycles of chemotherapy and fasting for the second half of cycles
Basic characteristics | Total 34 | Group A 18 (52.9%) | Group B 16 (47.1%) | Significance | |
|---|---|---|---|---|---|
Age at diagnosis | mean: 51.6 (SD 8.4) (median:51) Range: 28–69 | mean: 49.8 (SD 9.1) (median:51) (Range: 28–63 | mean: 53.6 (SD 7.3) (median: 52) Range:44–69 | 0.195 | |
Menopausal status | premenopausal | 24 | 13 (72.2) | 11 (68.7) | 0.824 |
postmenopausal | 10 | 5 (27.8) | 5 (31.3) | ||
Tumor entity | primary breast cancer | 25 (73.5) | 12 (66.7) | 13 (81.3) | 0.691 |
advanced breast cancer | 5 (14.7) | 3 (16.7) | 2 (12.5) | ||
ovarian cancer | 3 (8.8) | 2 (11.1) | 1 (6.3) | ||
advanced ovarian cancer | 1 (2.9) | 1 (5.6) | 0 (0.0) | ||
T-categories | T0 | 1 (2.9) | 0 (0.0) | 1 (6.3) | 0.323 |
T1 | 14 (41.2) | 7 (38.9) | 7 (43.8) | ||
T2 | 13 (38.2) | 9 (50.0) | 4 (25.0) | ||
T3 | 6 (17.6) | 2 (11.1) | 4 (25.0) | ||
Nodal status | pNx | 1 (2.9) | 1 (5.6) | 0 (0.0) | 0.434 |
pN0 | 16 (47.1) | 7 (38.9) | 9 (56.3) | ||
pN1 | 17 (50.0) | 10 (55.6) | 7 (43.8) | ||
Grading | G1 | 1 (2.9) | 1 (5.6) | 0 (0.0) | 0.298 |
G2 | 17 (50.0) | 7 (38.9) | 10 (62.5) | ||
G3 | 16 (47.1) | 10 (55.6) | 6 (37.5) | ||
Breast cancer intrinsic subtypes (n = 30) | Luminal A | 3 (10.0) | 3 (20.0) | 0 (0.0) | 0.098 |
Luminal B / HER2- | 11 (36.7) | 4 (26.7) | 7 (46.7) | ||
Luminal B / HER2+ | 4 (13.3) | 2 (13.3) | 2 (13.3) | ||
triple negative | 9 (30.0) | 6 (40.0) | 3 (20.0) | ||
HER2 overexpressing | 3 (10.0) | 0 (0.0) | 3 (20.0) | ||
Therapy (breast cancer) | CT | 25 (83.3) | 13 (86.7) | 12 (80.0) | 0.624 |
CT + Anti-HER2 | 5 (16.7) | 2 (13.3) | 3 (20.0) | ||
Therapy (ovarian cancer) | CT | 3 (75.0) | 3 (100.0) | 0 (0.0) | 0.046 |
CT + Anti-HER2 + Anti-VEGF | 1 (25.0) | 0 (0.0) | 1 (100.0) | ||
Body Mass Index | normal (BMI ≤25) | 19 (55.9) | 9 (50.0) | 10 (62.5) | 0.364 |
overweight (BMI: 25–30) | 13 (38.2) | 7 (38.9) | 6 (37.5) | ||
obese (BMI > 30) | 2 (5.9) | 2 (11.1) | 0 (0.0) |