Fig. 4
From: The oncogenic effects of HES1 on salivary adenoid cystic carcinoma cell growth and metastasis
HES1 knockdown inhibits tumorigenicity in vivo. a After being transfected with siRNA, the SACC cells were subcutaneously injected into the flanks of nude mice (n = 5), and the sizes of the resultant tumors were measured three times per week using a digital caliper. b The mice were placed and photographed; c The tumors were excised, photographed and weighed. D-E, The expression of HES1, Ki67, CASP3 and CASP9 was detected in the xenograft tumors by immunohistochemistry (d) (DAB, 400×) and the positive cells were counted and compared among the groups (e)