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Fig. 3 | BMC Cancer

Fig. 3

From: ZBP-89 and Sp1 contribute to Bak expression in hepatocellular carcinoma cells

Fig. 3

Sp1 overexpression induce Bak expression. In MIHA immortal non-tumour cells and HCC PLC/PRF/5 cells, Sp1 vector mediated upregulated expression increased Bak protein level, however, Sp3 overexpression did not affect Bak expression (a and b, * p < 0.05 compared with the corresponding control). In LO2 and HKCI-4 cells, Sp1 also increased Bak expression, but not Sp3 (C and D, * p < 0.05 compared with the corresponding control). RT-PCR results showed Sp1 not Sp3 induced Bak mRNA level up-regulation (E, * p < 0.05 compared with the corresponding control, 4-well repeated in triple experiments, data shown as Mean ± SE)

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