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Fig. 2 | BMC Cancer

Fig. 2

From: The impact of pharmacokinetic gene profiles across human cancers

Fig. 2

Clinical decision making is augmented by interpreted tumor genomics. a The clinical decision making cycle of therapy selection is multifaceted and can be informed by properly interpreted tumor genomics profiling. Developing high-confidence and mechanism-based algorithms for properly interpreting genomic information remains a clinical challenge. b We considered a set of rules based on tumor genomics features for interpreting somatic PK gene expression. From these rules, we developed a simple Therapy Efficacy model for interpreting if an administered therapy may be ineffective due to somatic PK gene expression

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