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Table 2 Patient characteristics in cohort 2

From: Survival after recurrence in patients with gastric cancer who receive S-1 adjuvant chemotherapy: exploratory analysis of the ACTS-GC trial

Cohort 2 IS group
(n = 189)
NIS group
(n = 103)
Χ square test
p-value
Sex Male 134 (70.9) 72 (69.9) 0.858
Female 55 (29.1) 31 (30.1)
Age (years)a <  60 60 (31.8) 38 (36.8) 0.199
60–69 68 (36.0) 42 (40.8)
70–81 61 (32.3) 23 (22.3)
Histologic type Differentiated 71 (37.6) 39 (37.9) 0.906
Undifferentiated 117 (61.9) 63 (61.2)
Others 1 (0.5) 1 (1.0)
Cancer stageb
(Japanese Classification)
II 64 (33.9) 25 (24.3) 0.226
IIIA 73 (38.6) 44 (42.7)
IIIB 52 (27.5) 34 (33.0)
Time from surgery to relapse (years) <  1 y 56 (29.6) 41 (39.8) 0.078
≥ 1 y 133 (70.4) 62 (60.2)
Site of first relapsec Local 16 (8.5) 2 (1.9) 0.027
Lymph nodes 51 (27.0) 24 (23.3) 0.491
Peritoneum 79 (41.8) 55 (53.4) 0.057
Hematogenous 63 (33.3) 36 (35.0) 0.780
  1. aAge at time of recurrence
  2. bCancer stage: Japanese Classification of Gastric Carcinoma (Second English Edition)
  3. cSome patients had initial recurrence at more than one site