Table 1 Patient characteristics in cohort 1
Cohort 1 | S-1 adjuvant (n = 160) | Surgery only (n = 215) | Χ square test p-value | |
|---|---|---|---|---|
Sex | Male | 111 (69.4) | 148 (68.8) | 0.911 |
Female | 49 (30.6) | 67 (31.2) | ||
Age (years)a | < 60 | 45 (28.1) | 67 (31.2) | 0.577 |
60–69 | 57 (35.6) | 81 (37.7) | ||
70–81 | 58 (36.3) | 67 (31.2) | ||
Histologic type | Differentiated | 62 (38.8) | 74 (34.4) | 0.345 |
Undifferentiated | 98 (61.3) | 139 (64.7) | ||
Others | 0 (0.0) | 2 (0.9) | ||
Cancer stageb (Japanese Classification) | II | 39 (24.4) | 67 (31.2) | 0.143 |
IIIA | 68 (42.5) | 95 (44.2) | ||
IIIB | 53 (33.1) | 53 (24.7) | ||
Site of first relapsec | Local | 11 (6.9) | 17 (7.9) | 0.707 |
Lymph nodes | 30 (18.8) | 53 (24.7) | 0.173 | |
Peritoneum | 76 (47.5) | 97 (45.1) | 0.647 | |
Hematogenous | 59 (36.9) | 69 (32.1) | 0.334 | |
Treatment after relapse | ||||
Chemotherapy | Yes | 121 (75.6) | 171 (79.5) | 0.367 |
No | 39 (24.4) | 44 (20.5) | ||
Chemotherapy including S-1 | Yes | 57 (35.6) | 132 (61.4) | < 0.001 |
No | 103 (64.4) | 83 (38.6) | ||
Surgery | Yes | 13 (8.1) | 23 (10.7) | 0.403 |
No | 147 (91.9) | 192 (89.3) | ||
Radiotherapy | Yes | 5 (3.1) | 4 (1.9) | 0.429 |
No | 155 (96.9) | 211 (98.1) | ||