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Table 1 Patient characteristics

From: Stereotactic body radiation therapy using a respiratory-gated volumetric-modulated arc therapy technique for small hepatocellular carcinoma

Variables

No. of patients (%)

Sex

 Male

97 (81.5)

 Female

22 (18.5)

Age (years)

 Median (range)

60 (36–90)

ECOG performance status

 0

102 (85.7)

 1

13 (10.9)

 2

4 (3.4)

Child-Pugh class

 A

108 (90.8)

 B

11 (9.2)

Viral aetiology

 Hepatitis B virus

93 (78.2)

 Hepatitis C virus

11 (9.2)

 Non B, Non C

15 (12.6)

Tumor size (cm)a

 Median

1.7

 0.8–1.0

8 (5.8)

 1.1–2.0

90 (64.7)

 2.1–3.0

32 (23.0)

 3.1–4.0

8 (5.8)

 5.1–6.0

1 (0.7)

Modified UICC stageb

 I

60 (50.4)

 II

53 (44.5)

 III

6 (5.0)

Alpha-fetoprotein (ng/mL)

 Range

1.6–4303.6

PIVKA-II (mAU/mL)

 Range

0–11,501.0

No. of prior treatment before SBRT

 Median (Range)

3 (0–25)

Summary of prior treatments

 None

3 (2.5)

 TACE

57 (47.9)

 TACE, RFA

27 (22.7)

 TACE, PEI

3 (2.5)

 TACE, RFA, PEI

1 (0.8)

 TACE, sorafenib

1 (0.8)

 Resection

2 (1.7)

 Resection, TACE

15 (12.6)

 Resection, TACE, RFA

5 (4.2)

 Resection, TACE, PEI

2 (1.7)

 Resection, RFA

2 (1.7)

 PEI

1 (0.8)

  1. ECOG Eastern Cooperative Oncology Group, UICC Union for International Cancer Control, PIVKA-II prothrombin induced by vitamin K absence-II, SBRT stereotactic body radiation therapy, TACE transarterial chemoembolization, RFA radiofrequency ablation, PEI percutaneous ethanol injection
  2. aOne hundred and thirty-nine tumors were analysed for size
  3. bModified UICC stage was assessed by the viable tumor at the timing of SBRT