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Table 3 Multivariate analysis using the Cox proportional hazard model of possible predictors of recurrence-free, overall and cancer-specific survivals after surgical treatments for localized renal cell carcinoma

From: Outcomes of pathologic stage T3a renal cell carcinoma up-staged from small renal tumor: emphasis on partial nephrectomy

 

Recurrence-free survival

Overall survival

Cancer-specific survival

HR

95% CI

p value

HR

95% CI

p value

HR

95% CI

p value

Age

1.010

0.996–1.023

0.153

1.067

1.049–1.085

<  0.001

1.052

1.027–1.077

<  0.001

BMI (≥24 kg/m2)

0.834

0.623–1.115

0.219

0.682

0.491–0.948

0.023

0.732

0.451–1.189

0.207

Gender (Female)

0.832

0.592–1.168

0.288

0.834

0.574–1.210

0.339

0.842

0.494–1.437

0.529

Diabetes mellitus (yes)

0.930

0.599–1.443

0.746

1.797

1.244–2.595

0.002

2.124

1.251–3.606

0.005

Hypertension (yes)

1.094

0.792–1.510

0.586

1.022

0.717–1.457

0.903

1.110

0.651–1.894

0.701

ECOG score (≥1)

2.024

1.114–3.678

0.021

2.031

1.456–2.835

<  0.001

1.029

0.368–2.877

0.956

Tumour size

1.298

1.206–1.397

<  0.001

1.256

1.150–1.372

<  0.001

1.461

1.305–1.635

<  0.001

Fuhrman grade (≥3)

1.557

1.160–2.089

0.003

0.841

0.606–1.167

0.299

1.128

0.699–1.822

0.621

Pathologic up-staging to T3a

2.195

1.459–3.300

<  0.001

1.632

1.029–2.588

0.037

2.238

1.252–4.003

0.007

Cellular type (non-clear cell)

0.720

0.463–1.119

0.144

1.120

0.699–1.795

0.638

1.009

0.494–2.059

0.981

  1. HR hazard ratio, CI confidence interval, BMI body mass index, ECOG Eastern Cooperative Oncology Group