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Table 3 Multivariate analysis using the Cox proportional hazard model of possible predictors of recurrence-free, overall and cancer-specific survivals after surgical treatments for localized renal cell carcinoma

From: Outcomes of pathologic stage T3a renal cell carcinoma up-staged from small renal tumor: emphasis on partial nephrectomy

  Recurrence-free survival Overall survival Cancer-specific survival
HR 95% CI p value HR 95% CI p value HR 95% CI p value
Age 1.010 0.996–1.023 0.153 1.067 1.049–1.085 <  0.001 1.052 1.027–1.077 <  0.001
BMI (≥24 kg/m2) 0.834 0.623–1.115 0.219 0.682 0.491–0.948 0.023 0.732 0.451–1.189 0.207
Gender (Female) 0.832 0.592–1.168 0.288 0.834 0.574–1.210 0.339 0.842 0.494–1.437 0.529
Diabetes mellitus (yes) 0.930 0.599–1.443 0.746 1.797 1.244–2.595 0.002 2.124 1.251–3.606 0.005
Hypertension (yes) 1.094 0.792–1.510 0.586 1.022 0.717–1.457 0.903 1.110 0.651–1.894 0.701
ECOG score (≥1) 2.024 1.114–3.678 0.021 2.031 1.456–2.835 <  0.001 1.029 0.368–2.877 0.956
Tumour size 1.298 1.206–1.397 <  0.001 1.256 1.150–1.372 <  0.001 1.461 1.305–1.635 <  0.001
Fuhrman grade (≥3) 1.557 1.160–2.089 0.003 0.841 0.606–1.167 0.299 1.128 0.699–1.822 0.621
Pathologic up-staging to T3a 2.195 1.459–3.300 <  0.001 1.632 1.029–2.588 0.037 2.238 1.252–4.003 0.007
Cellular type (non-clear cell) 0.720 0.463–1.119 0.144 1.120 0.699–1.795 0.638 1.009 0.494–2.059 0.981
  1. HR hazard ratio, CI confidence interval, BMI body mass index, ECOG Eastern Cooperative Oncology Group