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Table 1 Summarization of clinical and pathologic characteristics of entire patients and according to the up-staging of pathologic stages after surgical treatments for clinical stage T1 renal cell carcinoma

From: Outcomes of pathologic stage T3a renal cell carcinoma up-staged from small renal tumor: emphasis on partial nephrectomy

  Entire patients
(n = 3431)
Patients without up-staging
(n = 3216)
Patients with up-staging
(n = 215)
p value
Preoperative characteristics
 Median Age (y) 55.0 (46.0–65.0) 55.0 (46.0–65.0) 60 (52.0–69.0) <  0.001
 Median BMI (kg/m2) 24.6 (22.6–26.7) 24.6 (22.6–26.7) 24.4 (22.7–26.7) 0.406
 Gender (male) 2462 (72%) 2304 (72%) 158 (74%) 0.585
 ECOG score (≥1) 802 (23%) 749 (23%) 53 (25%) 0.677
 Diabetes mellitus 502 (15%) 459 (14%) 43 (20%) 0.028
 Hypertension 1351 (40%) 1244 (39%) 107 (50%) 0.001
 Tumour size (cm) 3.3 (2.0–4.4) 3.1 (1.9–4.1) 5.0 (3.7–6.2) <  0.001
 Laparoscopy 1420 (41%) 1355 (42%) 85 (40%) 0.617
 Type of nephrectomy     <  0.001
  Radical 1360 (40%) 1202 (37%) 158 (74%)  
  Partial 2071 (60%) 2014 (63%) 57 (27%)  
 Hilar location 210 (6.1%) 174 (5.4%) 36 (17%) <  0.001
 Tumour location     0.204
  Exophytic 1678 (49%) 1565 (49%) 113 (53%)  
  Mesophytic 809 (24%) 769 (24%) 40 (19%)  
  Endophytic 944 (28%) 882 (27%) 62 (29%)  
 Clinical stages     <  0.001
  cT1a 2462 (72%) 2379 (74%) 83 (39%)  
  cT1b 969 (28%) 837 (26%) 132 (61%)  
Postoperative characteristics
 Pathologic stage     <  0.001
  pT1 2406 (70%) 2406 (75%)   
  pT2 810 (24%) 810 (25%)   
  pT3a 215 (6.3%)   215 (100%)  
 Fuhrman grade     <  0.001
  ≤2 1935 (56%) 1865 (58%) 70 (33%)  
  ≥3 1496 (44%) 1351 (42%) 145 (67%)  
 Histologic subtype     0.234
  Clear cell 2912 (85%) 2737 (85%) 175 (81%)  
  Papillary 238 (6.9%) 223 (6.9%) 15 (7.0%)  
  Chromophobe 236 (6.9%) 217 (6.7%) 19 (8.8%)  
  Collecting duct 6 (0.2%) 5 (0.2%) 1 (0.5%)  
  Unclassified 39 (1.1%) 34 (1.1%) 5 (0.1%)  
  1. BMI body mass index, ECOG Eastern Cooperative Oncology Group