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Table 5 Cox univariate analysis for overall survival, with a time dependency added to CYFRA 21-1 pre-treatment and post-treatment levels

From: Prognostic value of serum CYFRA 21-1 1 in patients with anal canal squamous cell carcinoma treated with radio(chemo)therapy

 

Univariate analysis

HR [95%CI]

p

Age at diagnosis (> vs. ≤ 65 years)

2.13 [0.81;5.61]

0.12

Gender (male/female)

0.52 [0.16;3.07]

0.30

T stage (T3/T4 vs. T1/T2)

5.44 [1.36;16.48]

0.007

Nodal status (positive/negative)

1.34 [0.49;3.63]

0.56

Clinical stage (IIIA/IIIB vs. I/II)

2.72 [0.78;9.46]

0.12

Chemotherapy associated with radiation therapy (yes/no)

0.79 [0.28;2.27]

0.67

CYFRA 21-1 levels (elevated /normal)

Pre-treatment

5.99 [0.80;45.22]

0.08

Post-treatment

4.05 [1.49;10.95]

0.006