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Table 3 Pre-treatment and post-treatment serum CYFRA 21-1 levels according initial response to radiation-based therapy and long term treatment failure (defined as partial response or recurrence after complete response to initial radiation-based therapy)

From: Prognostic value of serum CYFRA 21-1 1 in patients with anal canal squamous cell carcinoma treated with radio(chemo)therapy

Initial response to radiation-based therapy Complete response Partial response Chi2 (p)
 n (%) 77 (93.9) 5 (6.1)  
Pre-treatment
 Normal (≤ 1 ng/ml) 22 (28.6) 0 (0)  
 Elevated (>  1 ng/ml) 55 (71.4) 5 (100) 1.95 (p = 0.32)
Post-treatment
 Normal (≤ 1 ng/ml) 53 (71) 0 (0)  
 Elevated (>  1 ng/ml) 24 (29) 5 (100) 9.73 (p = 0.004)
Long term treatment failure No Yes Chi2 (p)
 n (%) 62 (75.6) 20 (24.4)  
Pre-treatment
 Normal (≤ 1 ng/ml) 19 (30.6) 3 (15)  
 Elevated (>  1 ng/ml) 43 (69.4) 17 (85) 1.89 (p = 0.25)
Post-treatment
 Normal (≤ 1 ng/ml) 44 (71) 9 (45)  
 Elevated (>  1 ng/ml) 18 (29) 11 (55) 4.46 (p = 0.06)