Table 3 Pre-treatment and post-treatment serum CYFRA 21-1 levels according initial response to radiation-based therapy and long term treatment failure (defined as partial response or recurrence after complete response to initial radiation-based therapy)
Initial response to radiation-based therapy | Complete response | Partial response | Chi2 (p) |
n (%) | 77 (93.9) | 5 (6.1) | |
Pre-treatment | |||
Normal (≤ 1 ng/ml) | 22 (28.6) | 0 (0) | |
Elevated (> 1 ng/ml) | 55 (71.4) | 5 (100) | 1.95 (p = 0.32) |
Post-treatment | |||
Normal (≤ 1 ng/ml) | 53 (71) | 0 (0) | |
Elevated (> 1 ng/ml) | 24 (29) | 5 (100) | 9.73 (p = 0.004) |
Long term treatment failure | No | Yes | Chi2 (p) |
n (%) | 62 (75.6) | 20 (24.4) | |
Pre-treatment | |||
Normal (≤ 1 ng/ml) | 19 (30.6) | 3 (15) | |
Elevated (> 1 ng/ml) | 43 (69.4) | 17 (85) | 1.89 (p = 0.25) |
Post-treatment | |||
Normal (≤ 1 ng/ml) | 44 (71) | 9 (45) | |
Elevated (> 1 ng/ml) | 18 (29) | 11 (55) | 4.46 (p = 0.06) |