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Table 1 Distribution of HPV infection with a single type and multiple types in women from the Yangtze River Delta region

From: Distribution of human papilloma virus genotype prevalence in invasive cervical carcinomas and precancerous lesions in the Yangtze River Delta area, China

Types

CIN1

CIN2

CIN3

ICC

Total

n

(%)

n

(%)

n

(%)

n

(%)

n

(%)

Total

751

 

425

 

753

 

252

 

2181

 

Total HPV (+)

666

(88.68)

392

(92.24)

701

(93.09)

222

(88.10)

1981

(90.83)

16

117

(17.57)

135

(34.44)

411

(58.63)

146

65.77)

809

(40.84)

58

167

(25.08)

95

(24.23)

129

(18.40)

20

(9.01)

411

(20.75)

52

184

(27.63)

75

(19.13)

93

(13.27)

19

(8.56)

371

(18.73)

33

59

(8.86)

47

(11.99)

104

(14.84)

15

(6.76)

225

(11.36)

18

41

(6.16)

20

(5.10)

32

(4.56)

27

(12.16)

120

(6.06)

31

38

(5.71)

29

(7.40)

54

(7.70)

9

(4.05)

130

(6.56)

53

38

(5.71)

25

(6.38)

37

(5.28)

12

(5.41)

112

(5.65)

68

34

(5.11)

16

(4.08)

27

(3.85)

10

(4.50)

87

(4.39)

39

32

(4.80)

11

(2.81)

12

(1.71)

7

(3.15)

62

(3.13)

51

31

(4.65)

11

(2.81)

6

(0.86)

2

(0.90)

50

(2.52)

66

30

(4.50)

8

(2.04)

10

(1.43)

1

(0.45)

49

(2.47)

56

30

(4.50)

4

(1.02)

7

(1.00)

1

(0.45)

42

(2.12)

35

10

(1.50)

8

(2.04)

5

(0.71)

1

(0.45)

24

(1.21)

CP

49

(7.36)

25

(6.38)

28

(3.99)

10

(4.50)

112

(5.65)

11

15

(2.25)

5

(1.28)

9

(1.28)

4

(1.80)

33

(1.67)

6

7

(1.05)

9

(2.30)

5

(0.71)

1

(0.45)

22

(1.11)

42

7

(1.05)

2

(0.51)

5

(0.71)

3

(1.35)

17

(0.86)

  1. Note: Upright letters indicate HR-HPV’ italics indicate LR-HPV. HPV types with the frequency less than 1% are not shown
  2. The proportion of HPV16 type in ICC is significantly different from that of other high-risk type HPV, P<0.01 (HPV58, χ2=173.40; HPV52, χ2=176.60; HPV33, χ23=189.83; HPV18, χ2=152.27; HPV31, χ2=211.23; HPV53, χ2=200.26; HPV68, χ2=207.55; HPV39, χ2=218.76; HPV51, χ2=238.59; HPV66, χ2=242.74; HPV56, χ2=242.74; HPV35, χ2=242.74)
  3. The proportion of HPV18 type in ICC is significantly different from that of other high-risk type HPV, p<0.01 (HPV16, χ2=152.27; HPV31, χ2=11.13,; HPV53, χ2=7.16; HPV68, χ2=9.68; HPV39, χ2=14.47;HPV51, χ2=26.17; HPV66, χ2=29.25; HPV56, χ2=29.25;HPV35, χ2=29.25), except HPV58,52 and 33 type (HPV58, χ2=1.32, P>0.05, HPV52, χ2=1.76, p>0.05; HPV33, χ2=4.29, 0.01<p<0.05)
  4. The proportion of HPV58 type in ICC is significantly different from that of other high-risk type HPV, P<0.01 (HPV16, χ2=173.40; HPV39, χ2=7.58; HPV51, χ2=17.60; HPV66, χ2=20.49; HPV56, χ2=20.49; HPV35, χ2=20.49), except HPV52,33,18,53 type (HPV52, χ2=0.03; HPV33, χ2=0.88; HPV18, χ2=1.32; HPV53, χ2=2.44), p>0.05 and HPV31, 68 type (HPV31, χ2=5.08; HPV68, χ2=4.07), 0.01<p<0.05
  5. The proportion of HPV16 type in CIN3 is significantly different from that of other high-risk type HPV, P<0.01 (HPV58, χ2=257.32;HPV52, χ2=336.43; HPV33, χ23=310.65; HPV18, χ2=509.30; HPV31, χ2=440.58; HPV53, χ2=492.83; HPV68, χ2=525.97; HPV39, χ2=579.00; HPV51, χ2=601.28; HPV66, χ2=586.26; HPV56, χ2=597.56; HPV35, χ2=605.29)
  6. The proportion of HPV58 type in CIN3 is significantly different from that of other high-risk type HPV, P<0.01 (HPV16, χ2=257.32; HPV52, χ2=7.43; HPV18, χ2=70.97; HPV31, χ2=37.99; HPV53, χ2=62.09; HPV68, χ2=80.61; HPV39, χ2=115.96; HPV51, χ2=133.10; HPV66, χ2=121.39; HPV56, χ2=130.14; HPV35, χ2=136.33), except HPV33 (HPV33, χ2=3.44), p>0.05
  7. The proportion of HPV52 type in CIN3 is significantly different from that of other high-risk type HPV, P>0.01 (HPV16, χ2=336.43; HPV58, χ2=7.43; HPV18, χ2=35.17; HPV31, χ2=12.45; HPV53, χ2=28.56; HPV68, χ2=42.68; HPV39, χ2=72.61; HPV51, χ2=88.31; HPV66, χ2=77.51; HPV56, χ2=85.55; HPV35, χ2=91.36), except HPV33 (HPV33, χ2=0.77), p>0.05
  8. The proportion of HPV16 type in CIN2 is significantly different from that of other high-risk type HPV, P<0.01 (HPV58, χ2=10.69; HPV52, χ2=25.40; HPV33, χ2=60.08; HPV18, χ2=115.33; HPV31, χ2=93.92; HPV53, χ2=103.00; HPV68, χ2=125.96; HPV39, χ2=140.27; HPV51, χ2=140.27; HPV66, χ2=149.58; HPV56, χ2=162.71; HPV35, χ2=149.58)
  9. The proportion of HPV58 type in CIN2 is significantly different from that of other high-risk type HPV, P<0.01 (HPV16, χ2=10.69; HPV33, χ2=21.47; HPV18, χ2=62.14; HPV31, χ2=45.21; HPV53, χ2=52.23; HPV68, χ2=70.00; HPV39, χ2=83.39; HPV51, χ2=83.39; HPV66, χ2=91.71; HPV56, χ2=103.77; HPV35, χ2=91.71), except HPV52 (HPV52, χ2=3.26), p>0.05
  10. The proportion of HPV52 type in CIN2 is significantly different from that of other high-risk type HPV, P<0.01 (HPV16, χ2=25.40; HPV33, χ2=8.25; HPV18, χ2=39.29; HPV31, χ2=25.41; HPV53, χ2=31.04; HPV68, χ2=46.92; HPV39, χ2=57.95; HPV51, χ2=57.95; HPV66, χ2=65.58; HPV56, χ2=76.93; HPV35, χ2=65.58), except HPV58 (HPV58, χ2=3.26), p>0.05
  11. The proportion of HPV16 type in CIN1 is significantly different from that of other high-risk type HPV, P<0.01 (HPV58, χ2=12.62; HPV52, χ2=21.72; HPV33, χ2=24.84; HPV18, χ2=46.75; HPV31, χ2=51.35; HPV53, χ2=51.35; HPV68, χ2=57.98; HPV39, χ2=61.64; HPV51, χ2=63.47; HPV66, χ2=65.34; HPV56, χ2=65.34; HPV35, χ2=112.42)
  12. The proportion of HPV58 type in CIN1 is significantly different from that of other high-risk type HPV, P<0.01 (HPV16, χ2=12.62; HPV33, χ2=70.11; HPV18, χ2=101.98; HPV31, χ2=108.17; HPV53, χ2=108.17; HPV68, χ2=116.84; HPV39, χ2=121.53; HPV51, χ2=123.84; HPV66, χ2=126.19; HPV56, χ2=126.19; HPV35, χ2=181.18), except HPV52 (HPV52, χ2=1.26),p>0.05
  13. The proportion of HPV52 type in CIN1 is significantly different from that of other high-risk type HPV, P<0.01 (HPV16, χ2=21.72; HPV33, χ2=88.69; HPV18, χ2=123.28; HPV31, χ2=129.88; HPV53, χ2=129.88; HPV68, χ2=139.10; HPV39, χ2=144.06; HPV51, χ2=146.50; HPV66, χ2=148.98; HPV56, χ2=148.98; HPV35, χ2=206.04), except HPV58 (HPV58, χ2=1.26),p>0.05