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Table 2 Assessment method of administration of included studies

From: Evaluation of efficacy and safety for Brucea javanica oil emulsion in the control of the malignant pleural effusions via thoracic perfusion

Study

Trial

group

(N)

Control

group

(N)

Interventions (Groups)

Treatment cycle

Termination of treatment

Brucea javanica oil emulsion (BJOE) combined with chemotherapeutic agents

Chemotherapeutic agents alone

Guo Y 2004 [13]

30

30

Cisplatin 150 mg, 1/week

BJOE 50 mL, 1/week

Cisplatin 150 mg, 1/W

1 week

> 2 weeks, or

pleural effusion disappeared

Lei H 2006 [14]

31

30

Cisplatin 40-60 mg, 1/week

BJOE 40-60 mL, 1/week

Cisplatin 40-60 mg, 1/W

1 week

> 1 weeks, or

pleural effusion disappeared

Wang H 2007 [15]

35

35

Cisplatin 20-30 mg/m2, 1/week

BJOE 80-100 mL, 1/week

Cisplatin 20-30 mg/m2, 1/5-7D

1/5-7D

> 2 weeks, or

pleural effusion disappeared

Wu S 2009 [16]

68

55

Cisplatin 60 mg, 1/week

BJOE 50 mL, 1/week

Cisplatin 60 mg, 1/W

1 week

> 4 weeks, or

pleural effusion disappeared

Fu X 2009 [17]

60

60

Cisplatin 40/m2, 1/week

BJOE 100 mL, 1/week

Cisplatin 40/m2, 1/W

1 week

> 4 weeks, or

pleural effusion disappeared

Chen Y 2011 [18]

31

30

Cisplatin 60 mg, 1/week

BJOE 60 mL, 1/week

Cisplatin 60 mg, 1/W

1 week

> 4 weeks, or

pleural effusion disappeared

Jia L 2011 [19]

35

35

Oxaliplatin 100/m2, 1/week

BJOE 60 mL, 1/week

Oxaliplatin 100/m2, 1/W

1 week

> 4 weeks, or

pleural effusion disappeared

Liu B 2012 [20]

32

32

Cisplatin 40/m2, 1/week

BJOE 100 mL, 1/week

Cisplatin 40/m2, 1/W

1 week

> 4 weeks, or

pleural effusion disappeared

Zhang J 2012 [21]

28

36

Bleomycin 45-60 mg, 1/week

BJOE 80-100 mL, 1/week

Bleomycin 45-60 mg, 1/W

1 week

> 2 weeks, or

pleural effusion disappeared

Zhang H 2013 [22]

34

30

Cisplatin 40-60 mg, 1/week

BJOE 40-50 mL, 1/week

Cisplatin 40-60 mg, 1/W

1 week

> 2 weeks, or

pleural effusion disappeared

Yang G 2014 [23]

48

46

Cisplatin 40 mg/m2, 1/week

BJOE 80 mL, 1/week

Cisplatin 40 mg/m2, 1/W

1 week

> 3 weeks, or

pleural effusion disappeared

Yang H 2014 [24]

32

32

Cisplatin 40 mg/m2, 1/week

BJOE 50 mL/m2, 1/week

Cisplatin 40 mg/m2, 1/W

1 week

> 4 weeks, or

pleural effusion disappeared

Yue K 2016 [25]

60

50

Cisplatin 40 mg/m2, 1/week

BJOE 80-100 mL, 1/week

Cisplatin 80 mg/m2, 1/W

1 week

> 2 weeks, or

pleural effusion disappeared

Wang C 2016 [26]

45

45

Cisplatin 40 mg/m2, 1/week

BJOE 60 mL, 1/week

Cisplatin 40 mg/m2, 1/7d

7D/cycle,2 cycles

> 2 cycles, or

pleural effusion disappeared

  1. BJOE Brucea javanica oil emulsion, N numbers of patients, D day, W week