Fig. 4

Similarity of neoepitopes to human peptides. a. Matching status of top blastp hit(s) to a neoepitope’s gene of origin (see Methods) for patients across TCGA disease groups (gray = matching, red = non-matching). Vertical lines separate TCGA disease sites. Outliers have been removed for clarity. A disease abbreviation key is available in Additional file 1 Table S1. b. Distribution of the proportion of neoepitopes that matched to the gene of origin for each patient’s neoepitopes. On average, 77.3% of neoepitopes for each patient had a top blastp hit that matched their gene of origin