Occupational exposure to petroleum-based and oxygenated solvents and hypopharyngeal and laryngeal cancer in France: the ICARE study

Table 4 Association between hypopharyngeal and laryngeal cancers and exposure to combinations of petroleum-based solvents

Exposure to petroleum-based solvents	Controls n = 2536	Hypopharynx n = 313		Larynx n = 396
Exposure to petroleum-based solvents	n	n	OR^a [95% CI]	n	OR^a [95% CI]
None	1231	95	1	143	1
White spirits	316	46	1.40 [0.85–2.32]	55	0.98 [0.63–1.51]
Diesel	90	9	0.92 [0.41–2.11]	23	1.62 [0.89–2.96]
Ben, WS	74	19	1.55 [0.79–3.03]	26	1.27 [0.70–2.29]
WS, Diesel	242	44	1.47 [0.88–2.45]	46	0.90 [0.57–1.43]
Ben, SPP, WS	86	10	1.07 [0.47–2.45]	7	0.41 [0.17–1.00[
Gasoline, WS, Diesel	95	20	1.48 [0.75–2.90]	20	0.93 [0.50–1.73]
Ben, Gasoline, WS, Diesel	233	41	1.27 [0.75–2.15]	44	0.86 [0.54–1.39]
All petroleum-based solvents	55	15	2.12 [0.98–4.61]	14	1.28 [0.60–2.71]

Abbreviations: WS white spirits, diesel diesel, fuels and kerosene, ben benzene, SPP special petroleum products
^aOR adjusted for age at interview, residence area, alcohol consumption, smoking status, frequency and duration of smoking, exposure to asbestos

ISSN: 1471-2407