Skip to main content

Advertisement

Table 3 Association between hypopharyngeal and laryngeal cancers and occupational exposure to oxygenated solvents

From: Occupational exposure to petroleum-based and oxygenated solvents and hypopharyngeal and laryngeal cancer in France: the ICARE study

  Controls Hypopharynx Larynx
  n n ORa [95% CI] n ORa [95% CI]
Ketones and esters
 Never 2055 238   297  
 Ever 618 100 1.01 [0.74–1.37] 126 1.10 [0.84–1.45]
CEI
 Low 309 46 1.05 [0.71–1.56] 62 1.24 [0.88–1.75]
 Medium 245 38 0.89 [0.58–1.35] 53 1.08 [0.74–1.56]
 High 64 16 1.34 [0.70–2.59] 11 0.87 [0.42–1.79]
 p for trend     0.52    0.62
Alcohols
 Never 1775 225   290  
 Ever 898 113 0.95 [0.72–1.27] 133 0.90 [0.70–1.17]
CEI
 Low 447 45 0.85 [0.59–1.25] 64 0.99 [0.71–1.37]
 Medium 359 50 1.07 [0.74–1.55] 53 0.86 [0.60–1.22]
 High 91 17 1.25 [0.68–2.31] 16 0.93 [0.51–1.72]
 p for trend     0.31    0.87
Diethyl ether
 Never 2580 333   419  
 Ever 90 5 0.59 [0.20–1.70] 4 0.37 [0.12–1.11]
CEI
 Low 45 1 0.28 [0.04–2.19] 1 0.2 [0.03–1.53]
 Medium 36 4 1.41 [0.43–4.67] 3 0.73 [0.20–2.65]
 High 9 0 0
 p for trend     0.90    0.41
Ethylene glycol
 Never 2487 312   387  
 Ever 183 26 0.82 [0.49–1.36] 36 1.00 [0.64–1.56]
CEI
 Low 92 15 1.08 [0.57–2.04] 28 1.75 [1.04–2.94]
 Medium 72 11 0.83 [0.39–1.74] 6 0.39 [0.16–0.96]
 High 19 0 2 0.34 [0.07–1.64]
 p for trend     0.10    0.04
Tetrahydrofuran
 Never 2603 319   406  
 Ever 67 19 1.67 [0.87–3.21] 17 1.39 [0.73–2.63]
CEI
 Low 35 7 1.33 [0.53–3.35] 9 1.50 [0.66–3.35]
 Medium 26 8 1.57 [0.61–4.08] 8 1.62 [0.65–4.07]
 High 6 4 2.63 [0.55–12.65] 0
 p for trend     0.07    0.80
  1. Abbreviations: CEI Cumulative Exposure Index
  2. aOR adjusted for age at interview, residence area, alcohol consumption, smoking status, frequency and duration of smoking, exposure to asbestos