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Table 6 Allocation of cT1-T2 N0 patients based on their pathological N-status and CTSK protein expression

From: Cathepsin K associates with lymph node metastasis and poor prognosis in oral squamous cell carcinoma

  pN status Total
pN0 pN+
CTSK ≤25
> 25
8
6
1
9
9
15
Total 14 10 24
  1. The value of CTSK protein expression in predicting occult metastasis (≤25 predicts pN0, > 25 predicts pN+) in cT1-T2 N0 patients is calculated as follows: sensitivity (9/9 + 1) × 100% = 90%; specificity (8 + 6) × 100% =57%; positive predictive value (9/6 + 9) × 100% = 60%; negative predictive value (8/8 + 1) × 100% = 89%