Fig. 1
From: Cathepsin K associates with lymph node metastasis and poor prognosis in oral squamous cell carcinoma
Schematic representation of the work flow of this study. Previous studies resulted in the discovery and validation of a multi-gene signature. In this study, gene expression data were used to correlate the selected gene CTSK with clinical and histopathological parameters. From the same cohort of tumor samples, a TMA was constructed for immunohistochemical analysis of the selected gene to correlate their protein expression with clinical and histopathological parameters, and outcomes were compared