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Table 3 Univariate and multivariate Cox regression analysis of the relationship between clinical data and prognosis for TCGA dataset

From: Identification of methylation sites and signature genes with prognostic value for luminal breast cancer

Variable Univariate Cox Multivariable Cox
p-value HR(CI) p-value HR(CI)
Age (58.02 ± 13.28 y) 0.163 1.045(0.982~ 1.11)
ER (Positive/Negative) 0.174 0.225(0.0263~ 1.929)
HER2 (Positive/Negative) 0.289 3.51(0.345~ 5.71)
pathologic_M(M0/M1) 0.586 1.564(0.331~ 2.806)
pathologic_N (N0/N1/N2/N3) 0.639 1.159(0.625~ 2.15)
pathologic_T (T1/T2/T3/T4) 0.0915 1.821(0.909~ 2.652)
Stage (I/II/III/IV/V) 0.121 1.586(0.885~ 2.841)
Radiation therapy (Yes/No) 0.184 0.336(0.0673~ 1.679)
Luminal type (A/B) 0.03361 a 1.698(1.036–2.782) 0.0119 a 2.508(1.225~ 5.134)
PR (Positive/Negative) 0.00713 a 0.125(0.0274~ 0.568) 0.4649 0.725(0.306~ 1.718)
Riskscore 0.00115 a 1.095(1.037~ 1.156) 0.04382 a 1.229(0.729~ 2.071)
  1. aP values with significance