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Table 3 Univariate and multivariate Cox regression analysis of the relationship between clinical data and prognosis for TCGA dataset

From: Identification of methylation sites and signature genes with prognostic value for luminal breast cancer

Variable

Univariate Cox

Multivariable Cox

p-value

HR(CI)

p-value

HR(CI)

Age (58.02 ± 13.28 y)

0.163

1.045(0.982~ 1.11)

–

–

ER (Positive/Negative)

0.174

0.225(0.0263~ 1.929)

–

–

HER2 (Positive/Negative)

0.289

3.51(0.345~ 5.71)

–

–

pathologic_M(M0/M1)

0.586

1.564(0.331~ 2.806)

–

–

pathologic_N (N0/N1/N2/N3)

0.639

1.159(0.625~ 2.15)

–

–

pathologic_T (T1/T2/T3/T4)

0.0915

1.821(0.909~ 2.652)

–

–

Stage (I/II/III/IV/V)

0.121

1.586(0.885~ 2.841)

–

–

Radiation therapy (Yes/No)

0.184

0.336(0.0673~ 1.679)

–

–

Luminal type (A/B)

0.03361 a

1.698(1.036–2.782)

0.0119 a

2.508(1.225~ 5.134)

PR (Positive/Negative)

0.00713 a

0.125(0.0274~ 0.568)

0.4649

0.725(0.306~ 1.718)

Riskscore

0.00115 a

1.095(1.037~ 1.156)

0.04382 a

1.229(0.729~ 2.071)

  1. aP values with significance
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BMC Cancer

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