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Table 6 Within- and between-group changes in muscular strength and physical function over 12 weeks

From: Impact of resistance training on body composition and metabolic syndrome variables during androgen deprivation therapy for prostate cancer: a pilot randomized controlled trial

  Baseline Week 12 Within-group mean change over 12 weeksb Between-group mean change over 12 weeksc
Outcome n Mean ± SD n Mean ± SD Mean (95% CI) Mean (95% CI) P
Leg press (kg)a
 EXE 12 175.9 ± 78.2 12 288.7 ± 80.1 108.8 (74.1, 143.6) 106.5 (59.8, 153.1) < 0.01
 NoEXE 19 137.7 ± 68.6 19 130.3 ± 82.4 −9.2 (−35.0, 16.7)   
Chest press (kg) a
 EXE 13 25.5 ± 10.9 13 40.9 ± 16.0 15.1 (7.3, 23.0) 11.1 (0.1, 22.0) 0.048
 NoEXE 18 26.1 ± 13.3 18 26.4 ± 16.3 1.8 (−4.6, 8.2)   
Seated row (kg)a
 EXE 13 59.3 ± 12.9 13 81.9 ± 18.3 21.6 (17.4, 25.9) 20.1 (14.6, 25.7) < 0.01
 NoEXE 19 52.4 ± 13.3 19 50.4 ± 20.6 1.7 (−2.0, 5.4)   
Leg curl (kg) a
 EXE 13 81.4 ± 22.1 12 108.6 ± 25.4 24.5 (19.5, 29.6) 25.9 (7.7, 44.0) < 0.01
 NoEXE 18 73.6 ± 17.5 18 68.1 ± 24.5 0.2 (−4.4, 4.1)   
Shoulder press (kg) a
 EXE 13 13.5 ± 9.0 12 27.3 ± 13.1 10.9 (6.7, 15.0) 53.7 (18.6, 88.8) < 0.01
 NoEXE 18 12.1 ± 9.6 18 12.6 ± 11.1 0.7 (−2.5, 4.0)   
Leg extension (kg) a
 EXE 13 110.8 ± 43.6 13 178.4 ± 42.7 56.2 (36.0, 76.4) 8.4 (2.7, 14.2) < 0.01
 NoEXE 16 90.7 ± 24.4 16 89.4 ± 41.7 0.3 (−17.4, 16.9)   
400 m walk (s)
 EXE 11 248.5 ± 50.0 11 227.7 ± 46.7 −20.9 (−3.5, 45.4) −32.3 (−74.4, 9.8) 0.13
 NoEXE 15 257.9 ± 60.2 15 257.6 ± 79.0 1.9 (−23.2, 19.4)   
Timed up and go (s)
 EXE 12 5.5 ± 2.3 12 4.7 ± 1.8 −0.8 (−1.4, −0.3) −0.8 (− 1.6, 0.1) 0.07
 NoEXE 16 5.3 ± 1.8 16 5.6 ± 2.6 −0.3 (− 0.7, 0.2)   
Stair climb (s)
 EXE 11 2.2 ± 0.7 11 1.9 ± 0.5 −0.3 (−0.6, 0.03) −0.4(−1.0, 0.1) 0.14
 NoEXE 15 2.2 ± 0.8 15 2.3 ± 1.2 0.02 (−0.3, 0.3)   
  1. Data presented as mean ± standard deviation. P, significance level; EXE, exercise groups (TRAINPRO and TRAIN); NoEXE, non-exercise groups (PRO and STRETCH)
  2. aStrength values presented as estimated 1-repetition maximum (RM) values calculated from 10-RM tests
  3. bEXE relative to NoEXE adjusted for baseline values
  4. cEXE relative to NoEXE adjusted for baseline values, protein supplementation, body mass index and number of comorbidities