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Table 6 Within- and between-group changes in muscular strength and physical function over 12 weeks

From: Impact of resistance training on body composition and metabolic syndrome variables during androgen deprivation therapy for prostate cancer: a pilot randomized controlled trial

 

Baseline

Week 12

Within-group mean change over 12 weeksb

Between-group mean change over 12 weeksc

Outcome

n

Mean ± SD

n

Mean ± SD

Mean (95% CI)

Mean (95% CI)

P

Leg press (kg)a

 EXE

12

175.9 ± 78.2

12

288.7 ± 80.1

108.8 (74.1, 143.6)

106.5 (59.8, 153.1)

< 0.01

 NoEXE

19

137.7 ± 68.6

19

130.3 ± 82.4

−9.2 (−35.0, 16.7)

  

Chest press (kg) a

 EXE

13

25.5 ± 10.9

13

40.9 ± 16.0

15.1 (7.3, 23.0)

11.1 (0.1, 22.0)

0.048

 NoEXE

18

26.1 ± 13.3

18

26.4 ± 16.3

1.8 (−4.6, 8.2)

  

Seated row (kg)a

 EXE

13

59.3 ± 12.9

13

81.9 ± 18.3

21.6 (17.4, 25.9)

20.1 (14.6, 25.7)

< 0.01

 NoEXE

19

52.4 ± 13.3

19

50.4 ± 20.6

1.7 (−2.0, 5.4)

  

Leg curl (kg) a

 EXE

13

81.4 ± 22.1

12

108.6 ± 25.4

24.5 (19.5, 29.6)

25.9 (7.7, 44.0)

< 0.01

 NoEXE

18

73.6 ± 17.5

18

68.1 ± 24.5

0.2 (−4.4, 4.1)

  

Shoulder press (kg) a

 EXE

13

13.5 ± 9.0

12

27.3 ± 13.1

10.9 (6.7, 15.0)

53.7 (18.6, 88.8)

< 0.01

 NoEXE

18

12.1 ± 9.6

18

12.6 ± 11.1

0.7 (−2.5, 4.0)

  

Leg extension (kg) a

 EXE

13

110.8 ± 43.6

13

178.4 ± 42.7

56.2 (36.0, 76.4)

8.4 (2.7, 14.2)

< 0.01

 NoEXE

16

90.7 ± 24.4

16

89.4 ± 41.7

0.3 (−17.4, 16.9)

  

400 m walk (s)

 EXE

11

248.5 ± 50.0

11

227.7 ± 46.7

−20.9 (−3.5, 45.4)

−32.3 (−74.4, 9.8)

0.13

 NoEXE

15

257.9 ± 60.2

15

257.6 ± 79.0

1.9 (−23.2, 19.4)

  

Timed up and go (s)

 EXE

12

5.5 ± 2.3

12

4.7 ± 1.8

−0.8 (−1.4, −0.3)

−0.8 (− 1.6, 0.1)

0.07

 NoEXE

16

5.3 ± 1.8

16

5.6 ± 2.6

−0.3 (− 0.7, 0.2)

  

Stair climb (s)

 EXE

11

2.2 ± 0.7

11

1.9 ± 0.5

−0.3 (−0.6, 0.03)

−0.4(−1.0, 0.1)

0.14

 NoEXE

15

2.2 ± 0.8

15

2.3 ± 1.2

0.02 (−0.3, 0.3)

  
  1. Data presented as mean ± standard deviation. P, significance level; EXE, exercise groups (TRAINPRO and TRAIN); NoEXE, non-exercise groups (PRO and STRETCH)
  2. aStrength values presented as estimated 1-repetition maximum (RM) values calculated from 10-RM tests
  3. bEXE relative to NoEXE adjusted for baseline values
  4. cEXE relative to NoEXE adjusted for baseline values, protein supplementation, body mass index and number of comorbidities