BMC Cancer

Table 6 Univariate and multivariate analysis of survival on clinicopathological factors

From: The alterations of cytokeratin and vimentin protein expressions in primary esophageal spindle cell carcinoma

	Number	Univariate analysis			Multivariate analysis
	Number	HR	95% CI	P	HR	95% CI	P
Age
< 60 years	26	2.52	(1.03–6.16)	0.036	2.66	(1.06–6.63)	0.036
≥ 60 years	56	2.52	(1.03–6.16)	0.036	2.66	(1.06–6.63)	0.036
Gender
Male	57	0.77	(0.34–1.75)	0.537
Female	25	0.77	(0.34–1.75)	0.537
Family history
Positive	18	0.40	(0.12–1.31)	0.115
Negative	64	0.40	(0.12–1.31)	0.115
Smoking
Yes	41	0.71	(0.35–1.46)	0.348
No	41	0.71	(0.35–1.46)	0.348
Alcohol
Yes	36	1.07	(0.53–2.18)	0.850
No	46	1.07	(0.53–2.18)	0.850
Tumor location
Upper	3	1.96	(0.96–4.01)	0.109
Middle	54
Lower	25
Gross appearance
Polypoid	69	1.58	(0.90–2.77)	0.001	1.38	(0.79–2.39)	0.256
Ulcerative	8
Infiltrating	5
Lymph node metastasis
Yes	23	0.51	(0.24–1.08)	0.072
No	59	0.51	(0.24–1.08)	0.072
TNM stage
I	29	1.95	(1.18–3.21)	0.015	2.11	(1.28–3.50)	0.003
II	37
III	16
IV	0
AE1/AE3 protein
Positive	70	1.10	(0.83–1.45)	0.527
Negative	12	1.10	(0.83–1.45)	0.527
CK5/6 protein
Positive	63	1.82	(0.70–4.73)	0.222
Negative	19	1.82	(0.70–4.73)	0.222

Abbreviations: CI confidence interval, HR hazard ratio

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