| |
Number
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
HR
|
95% CI
|
P
|
HR
|
95% CI
|
P
|
|---|
|
Age
|
|
< 60 years
|
26
|
2.52
|
(1.03–6.16)
|
0.036
|
2.66
|
(1.06–6.63)
|
0.036
|
|
≥ 60 years
|
56
|
|
Gender
|
|
Male
|
57
|
0.77
|
(0.34–1.75)
|
0.537
| | | |
|
Female
|
25
|
|
Family history
|
|
Positive
|
18
|
0.40
|
(0.12–1.31)
|
0.115
| | | |
|
Negative
|
64
|
|
Smoking
|
|
Yes
|
41
|
0.71
|
(0.35–1.46)
|
0.348
| | | |
|
No
|
41
|
|
Alcohol
|
|
Yes
|
36
|
1.07
|
(0.53–2.18)
|
0.850
| | | |
|
No
|
46
|
|
Tumor location
|
|
Upper
|
3
|
1.96
|
(0.96–4.01)
|
0.109
| | | |
|
Middle
|
54
|
|
Lower
|
25
|
|
Gross appearance
|
|
Polypoid
|
69
|
1.58
|
(0.90–2.77)
|
0.001
|
1.38
|
(0.79–2.39)
|
0.256
|
|
Ulcerative
|
8
|
|
Infiltrating
|
5
|
|
Lymph node metastasis
|
|
Yes
|
23
|
0.51
|
(0.24–1.08)
|
0.072
| | | |
|
No
|
59
|
|
TNM stage
|
|
I
|
29
|
1.95
|
(1.18–3.21)
|
0.015
|
2.11
|
(1.28–3.50)
|
0.003
|
|
II
|
37
|
|
III
|
16
|
|
IV
|
0
|
|
AE1/AE3 protein
|
|
Positive
|
70
|
1.10
|
(0.83–1.45)
|
0.527
| | | |
|
Negative
|
12
|
|
CK5/6 protein
|
|
Positive
|
63
|
1.82
|
(0.70–4.73)
|
0.222
| | | |
|
Negative
|
19
|
- Abbreviations: CI confidence interval, HR hazard ratio
