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Table 6 Univariate and multivariate analysis of survival on clinicopathological factors

From: The alterations of cytokeratin and vimentin protein expressions in primary esophageal spindle cell carcinoma

  Number Univariate analysis Multivariate analysis
HR 95% CI P HR 95% CI P
Age
  < 60 years 26 2.52 (1.03–6.16) 0.036 2.66 (1.06–6.63) 0.036
  ≥ 60 years 56
Gender
 Male 57 0.77 (0.34–1.75) 0.537    
 Female 25
Family history
 Positive 18 0.40 (0.12–1.31) 0.115    
 Negative 64
Smoking
 Yes 41 0.71 (0.35–1.46) 0.348    
 No 41
Alcohol
 Yes 36 1.07 (0.53–2.18) 0.850    
 No 46
Tumor location
 Upper 3 1.96 (0.96–4.01) 0.109    
 Middle 54
 Lower 25
Gross appearance
 Polypoid 69 1.58 (0.90–2.77) 0.001 1.38 (0.79–2.39) 0.256
 Ulcerative 8
 Infiltrating 5
Lymph node metastasis
 Yes 23 0.51 (0.24–1.08) 0.072    
 No 59
TNM stage
 I 29 1.95 (1.18–3.21) 0.015 2.11 (1.28–3.50) 0.003
 II 37
 III 16
 IV 0
AE1/AE3 protein
 Positive 70 1.10 (0.83–1.45) 0.527    
 Negative 12
CK5/6 protein
 Positive 63 1.82 (0.70–4.73) 0.222    
 Negative 19
  1. Abbreviations: CI confidence interval, HR hazard ratio
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