Table 4 The expression rate of CK5/6 protein in PESC
Number | Expression rate of CK 5/6 protein (%) | χ 2 | P | ||
|---|---|---|---|---|---|
Positive(n = 63) | Negative(n = 19) | ||||
Age | |||||
< 60 years | 26 | 15 (57.7) | 11 (42.3) | 7.83 | 0.005 |
≥ 60 years | 56 | 48 (85.7) | 8 (14.3) | ||
Gender | |||||
Male | 57 | 43 (75.4) | 14 (24.6) | 0.20 | 0.652 |
Female | 25 | 20 (80.0) | 5 (20.0) | ||
Family history | |||||
Positive | 18 | 15 (83.3) | 3 (16.7) | 0.18 | 0.671 |
Negative | 64 | 48 (75.0) | 16 (25.0) | ||
Smoking | |||||
Yes | 41 | 30 (73.2) | 11 (26.8) | 0.62 | 0.432 |
No | 41 | 33 (80.5) | 8 (19.5) | ||
Alcohol | |||||
Yes | 36 | 26 (72.2) | 10 (27.8) | 0.77 | 0.382 |
No | 46 | 37 (80.4) | 9 (19.7) | ||
Tumor location | |||||
Upper | 3 | 2 (66.7) | 1 (33.3) | 2.87 | 0.267 |
Middle | 54 | 39 (72.2) | 15 (27.8) | ||
Lower | 25 | 22 (88.0) | 3 (12.0) | ||
Gross appearance | |||||
Polypoid | 69 | 53 (76.8) | 16 (23.2) | 2.08 | 0.350 |
Ulcerative | 8 | 5 (62.5) | 3 (37.5) | ||
Infiltrating | 5 | 5 (100.0) | 0 (0.0) | ||
Lymph node metastasis | |||||
Yes | 23 | 19 (82.6) | 4 (17.4) | 0.23 | 0.629 |
No | 59 | 44 (74.6) | 15 (25.4) | ||
TNM stage | |||||
I | 29 | 26 (89.7) | 3 (10.3) | 5.63 | 0.056 |
II | 37 | 24 (64.9) | 13 (35.1) | ||
III | 16 | 13 (81.3) | 3 (18.7) | ||
IV | 0 | 0 (0.0) | 0 (0.0) | ||