Fig. 1

Genetic alterations detected from 33 Chinese mCRC patients using targeted NGS with a 416 cancer-related gene panel. Twenty one genes with at least 4 recurrences are shown in the figure. PFS upon receiving cetuximab are shown on the top. Different mutation types are colour coded: cyan represents single nucleotide variant (SNV), orange represents copy number variation (CNV), and red represents insert/deletion (Indel). Patients received previous chemotherapy are labeled differently as indicated in their PFS