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Table 3 Univariate Cox regression analysis for PTC recurrence in the training and testing patient sets

From: Using a nomogram based on preoperative serum fibrinogen levels to predict recurrence of papillary thyroid carcinoma

  Training set   Testing set  
Factor HR(95% CI) p HR(95% CI) p
All patients 414   609  
Age (years)   0.622   0.753
  ≤45 1 (reference)   1 (reference)  
  >45 0.982 (0.457 to 1.452)   0.872(0.562 to 1.654)  
Age (years)   0.672   0.261
  ≤55 1 (reference)   1 (reference)  
  >55 1.524 (0.782 to 2.281)   1.622 (0.891 to 2.462)  
Gender   0.321   0.271
  Female 1 (reference)   1 (reference)  
  Male 1.451 (0.661 to 2.992)   1.652 (0.842 to 2.721)  
Postoperative RAI   0.172   0.283
  Yes 1 (reference)   1 (reference)  
  No 0.872 (0.521 to 1.726)   0.982 (0.475 to 2.228)  
Race   0.372   0.208
  Han 1 (reference)   1 (reference)  
  Other 1.211 (0.872 to 1.872)   1.253 (0.772 to 2.011)  
BRAF mutation   0.382   0.229
  Positive 1 (reference)   1 (reference)  
  Negative 0.871 (0.622 to 1.263)   0.982 (0.821 to 1.461)  
T classification   0.021   0.008
 T1-2 1 (reference)   1 (reference)  
 T3-4 3.261 (1.271 to 5.653)   3.876 (1.532 to 6.211)  
PTC nodule number   0.152   0.102
  Single 1 (reference)   1 (reference)  
  Multiple 1.933 (0.891 to 2.901)   2.011 (0.902 to 3.110)  
N classification   0.048   0.041
  N0 1 (reference)   1 (reference)  
  N1 1.502 (1.029 to 2.893)   1.462 (1.081 to 3.011)  
M classification   <0.001   <0.001
  M0 1 (reference)   1 (reference)  
  M1 8.662 (3.092 to 16.223)   9.920 (3.825 to 21.273)  
Serum fibrinogen levels   0.012   0.007
  Low 1 (reference)   1 (reference)  
  High 3.457 (2.203 to 6.782)   4.228(2.102 to 7.541)