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Table 3 Univariate and Multivariate Analysis of Variables Associated with Overall Survival (OS) in Patients with hilar cholangiocarcinoma

From: ADAM-17 is a poor prognostic indicator for patients with hilar cholangiocarcinoma and is regulated by FoxM1

Variable

No.

OS(months)

P

P

HR (multivariate)

95% CI

(univariate)

(multivariate)

Tumor stage

 T1–3

7

50

0.004

0.02

0.135

0.025–0.730

 T4

47

17

    

Regional lymph nodes positive

 No

18

42

0.006

0.023

0.384

0.168–0.875

 Yes

36

14

    

R

 R0

24

26

0.024

0.784

0.903

0.437–1.869

 R1–2

30

16

    

ADAM10

 Negative

16

50

0.01

0.589

1.359

0.447–4.135

 Positive

38

17

    

ADAM17

 Negative

19

42

0.003

0.035

0.318

0.109–0.924

 Positive

35

15