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Table 3 Univariate and Multivariate Analysis of Variables Associated with Overall Survival (OS) in Patients with hilar cholangiocarcinoma

From: ADAM-17 is a poor prognostic indicator for patients with hilar cholangiocarcinoma and is regulated by FoxM1

Variable No. OS(months) P P HR (multivariate) 95% CI
(univariate) (multivariate)
Tumor stage
 T1–3 7 50 0.004 0.02 0.135 0.025–0.730
 T4 47 17     
Regional lymph nodes positive
 No 18 42 0.006 0.023 0.384 0.168–0.875
 Yes 36 14     
R
 R0 24 26 0.024 0.784 0.903 0.437–1.869
 R1–2 30 16     
ADAM10
 Negative 16 50 0.01 0.589 1.359 0.447–4.135
 Positive 38 17     
ADAM17
 Negative 19 42 0.003 0.035 0.318 0.109–0.924
 Positive 35 15