Table 1 Clinicopathological characteristics of the 62 patients dichotomized by exon19 microdeletions and exon21 mutations
Total | Exon19 | Exon21 | p-value | ||
|---|---|---|---|---|---|
Number of patients | 62 (100%) | 37 (66.1%) | 25 (33.9%) | ||
Age (median, range) | 70.5 (28–86) | 67 (28–81) | 71 (48–86) | 0.088 | |
Gender | Male | 12 (19.4%) | 8 (21.6%) | 4 (16%) | 0.747 |
Female | 50 (80.6%) | 29 (78.4%) | 21 (84%) | ||
ECOG performance status | 0 | 24 (38.7%) | 17(46%) | 7(28%) | 0.182 |
1 | 32 (51.6%) | 17(46%) | 15(60%) | ||
2 | 6(9.7%) | 3(8%) | 3 (12%) | ||
Smoking status | Never-smoker | 42(67.7%) | 25 (67.5%) | 17 (68%) | 1.00 |
Ever smoker | 20(32.3%) | 12 (32.5%) | 8 (32%) | ||
Tumor Stage | IIIb | 6 (9.7%) | 1 (1.6%) | 5(20%) | 0.035 |
IV | 56 (90.3%) | 36(98.4%) | 20(80%) | ||