From: Modeling treatment-dependent glioma growth including a dormant tumor cell subpopulation
n X | number of cells of type X |
x X | ratio of cells of type X in population |
D, P | index for dormant or rapidly proliferating cell type, respectively |
ε | Fitness of dormant (D) cells |
λ | treatment cost on normally growing cells |
σ | probability for spontaneous conversion between types |
\( \overline{f} \) | total average fitness of all cell types in the population |